2016
DOI: 10.1590/0102-6720201600030009
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Abstract: Background: Surgical trauma triggers an important postoperative stress response characterized by significantly elevated levels of cytokines, an event that can favor the emergence of immune disorders which lead to disturbances in the patient's body defense. The magnitude of postoperative stress is related to the degree of surgical trauma. Aim: To evaluate the expression of pro-inflammatory (TNF-α, IFN-γ, IL-1β, and IL-17) and anti-inflammatory (IL-4) cytokines in patients submitted to conventional and single-po… Show more

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Cited by 10 publications
(9 citation statements)
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“…For cases that presented granulomas, they were removed using local anesthesia and small surgical exploration with resolution of 100% of the cases. These minor complications were found with values ​​very close to that found in the literature 11 , 16 , 29 , 30 .…”
Section: Discussionsupporting
confidence: 88%
See 1 more Smart Citation
“…For cases that presented granulomas, they were removed using local anesthesia and small surgical exploration with resolution of 100% of the cases. These minor complications were found with values ​​very close to that found in the literature 11 , 16 , 29 , 30 .…”
Section: Discussionsupporting
confidence: 88%
“…The mean surgical time observed was approximately 68 min and is within the mean found in the literature for MPLS and single port cholecystectomies, evidencing that the single port operation did not cause any impairment in relation to anesthetic time, increase of drugs used, longer time on surgery room and greater risk associated to the surgical time 1 , 3 , 4 , 11 , 13 , 16 , 18 , 21 , 26 , 27 .…”
Section: Discussionsupporting
confidence: 72%
“…It was made for the first time in 1987 by Muret. Despite many modified methods (natural orifice transluminal endoscopic surgery - NOTES -, single-incision laparoscopic surgery 3 ), LC is still the gold standard for symptomatic gallstone disease 4 .…”
Section: Introductionmentioning
confidence: 99%
“…It is estimated, nowadays, that 85% of the patients with cholecystolithiasis keep asymptomatic for at least 10 years. In the last two decades, the knowledge and management evolved in a meaningful way, and a lot of clinical and microbiological parameters have been studied, just like the way how antibiotics and defense systems of biliary tract interfere with the evolution of the infections in bile duct 1 , 4 , 10 , 11 .…”
Section: Introductionmentioning
confidence: 99%