Compact 5-LEDs illumination system for multi-spectral surface plasmon resonance sensing

Середа, А. П.; Moreau, Julien; Boulade, Marine; Olivéro, Aurore; Canva, Michael; Maillart, Emmanuel

doi:10.1016/j.snb.2014.11.080

Cited by 12 publications

(9 citation statements)

References 16 publications

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“…Multispectral SPRi was also built up using five color LEDs integrated into an optical fiber and illuminating the sensing layer through a Kretschmann configuration. By performing a DNA hybridization measurement, an impressive LOD of 3 × 10 −6 RIU had been achieved [ 82 ]. Another captivating notion implemented a commercial LED light source in an SPR sensor for the Hg 2+ detection in pure and tap water, respectively.…”

Section: Light Source and Platform Preferences For Spr Sensormentioning

confidence: 99%

Surface Plasmon Resonance Optical Sensor: A Review on Light Source Technology

2018

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The notion of surface plasmon resonance (SPR) sensor research emerged more than eight decades ago from the first observed phenomena in 1902 until the first introduced principles for gas sensing and biosensing in 1983. The sensing platform has been hand-in-hand with the plethora of sensing technology advancement including nanostructuring, optical technology, fluidic technology, and light source technology, which contribute to substantial progress in SPR sensor evolution. Nevertheless, the commercial products of SPR sensors in the market still require high-cost investment, component, and operation, leading to unaffordability for their implementation in a low-cost point of care (PoC) or laboratories. In this article, we present a comprehensive review of SPR sensor development including the state of the art from a perspective of light source technology trends. Based on our review, the trend of SPR sensor configurations, as well as its methodology and optical designs are strongly influenced by the development of light source technology as a critical component. These simultaneously offer new underlying principles of SPR sensor towards miniaturization, portability, and disposability features. The low-cost solid-state light source technology, such as laser diode, light-emitting diode (LED), organic light emitting diode (OLED) and smartphone display have been reported as proof of concept for the future of low-cost SPR sensor platforms. Finally, this review provides a comprehensive overview, particularly for SPR sensor designers, including emerging engineers or experts in this field.

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Section: Light Source and Platform Preferences For Spr Sensormentioning

confidence: 99%

Surface Plasmon Resonance Optical Sensor: A Review on Light Source Technology

2018

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“…Sereda et al propose a multispectral setup that utilizes 5 LEDs of various color for excitation. 50 As these light sources are sequentially lit, images for each are generated which can be analyzed for the construction of location-specific wavelength reflectivity curves, with the measurement time of each being ca. 10 s. Shao and co-workers were able to streamline this setup through the use of a white light source and a liquid crystal tunable filter (LCTF), which is capable of selectively allowing specific wavelengths of light to pass through and is electronically controlled.…”

Section: Platforms and Instrumentationmentioning

confidence: 99%

Surface Plasmon Resonance: Material and Interface Design for Universal Accessibility

2017

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“…The surface plasmon resonance (SPR) sensing technique, which offers unique real-time and label-free measurement capabilities with high detection sensitivity, has become an important tool for exploring the kinetics of biomolecular interactions and has been widely used to detect chemical and biological analytes [ 1 , 2 , 3 , 4 ]. By combining the SPR approach with an imaging system, high-throughput, real-time, label-free biosensing in 2D microarrays and parallel monitoring of a multiple number of biomolecular interactions can be achieved [ 5 , 6 , 7 , 8 , 9 ]. However, to become a potential candidate to replace the well-established fluorescence-based microarray technique, which suffers from photobleaching and the lack of quantitative information, the data capture speed and detection sensitivity of the SPR imaging approach need to be further improved.…”

Section: Introductionmentioning

confidence: 99%

Wavelength-Scanning SPR Imaging Sensors Based on an Acousto-Optic Tunable Filter and a White Light Laser

Zeng

Wang

et al. 2017

Sensors

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A fast surface plasmon resonance (SPR) imaging biosensor system based on wavelength interrogation using an acousto-optic tunable filter (AOTF) and a white light laser is presented. The system combines the merits of a wide-dynamic detection range and high sensitivity offered by the spectral approach with multiplexed high-throughput data collection and a two-dimensional (2D) biosensor array. The key feature is the use of AOTF to realize wavelength scan from a white laser source and thus to achieve fast tracking of the SPR dip movement caused by target molecules binding to the sensor surface. Experimental results show that the system is capable of completing a SPR dip measurement within 0.35 s. To the best of our knowledge, this is the fastest time ever reported in the literature for imaging spectral interrogation. Based on a spectral window with a width of approximately 100 nm, a dynamic detection range and resolution of 4.63 × 10−2 refractive index unit (RIU) and 1.27 × 10−6 RIU achieved in a 2D-array sensor is reported here. The spectral SPR imaging sensor scheme has the capability of performing fast high-throughput detection of biomolecular interactions from 2D sensor arrays. The design has no mechanical moving parts, thus making the scheme completely solid-state.

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Compact 5-LEDs illumination system for multi-spectral surface plasmon resonance sensing

Cited by 12 publications

References 16 publications

Surface Plasmon Resonance Optical Sensor: A Review on Light Source Technology

Surface Plasmon Resonance Optical Sensor: A Review on Light Source Technology

Surface Plasmon Resonance: Material and Interface Design for Universal Accessibility

Wavelength-Scanning SPR Imaging Sensors Based on an Acousto-Optic Tunable Filter and a White Light Laser

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