Commonly Used Intraocular Medications and the Corneal Endothelium

Investigation of the effects of intracameral carbachol on oxidative stress and apoptosis in rat corneas

“…Vaughn et al [7] found that carbachol had no effect on corneal thickness. Olson et al [16] showed that carbachol and commonly used intraocular medications had no significant effect on specular microscopy and the corneal endothelial in cats. Akiyama et al [17] investigated the effects of acetylcholine, carbachol, and mannitol on corneal endothelial function in rabbits.…”

Investigation of the effects of intracameral carbachol on oxidative stress and apoptosis in rat corneas

“…Vaughn et al [7] found that carbachol had no effect on corneal thickness. Olson et al [16] showed that carbachol and commonly used intraocular medications had no significant effect on specular microscopy and the corneal endothelial in cats. Akiyama et al [17] investigated the effects of acetylcholine, carbachol, and mannitol on corneal endothelial function in rabbits.…”

Presumed herpetic endotheliitis following phacoemulsification surgery*

“…Pseudophakic bullous keratopathy occurring after cataract surgery is usually attributed to either pre‐existing low corneal endothelial cell counts 2 and diseases like Fuch’s endothelial dystrophy 3 or surgery‐induced insult to an otherwise normal corneal endothelium due to various factors 4–12 …”

Maintenance of Mydriasis with One Bolus of Epinephrine Injection During Phacoemulsification

“…However, systemic absorption of epinephrine during the operation may cause systemic side effects, such as elevated heart rate and blood pressure (4). Moreover, several studies reported that intracameral injection of high concentration epinephrine might lead to corneal injury (5)(6)(7). The purpose of the present study was to investigate the lowest concentration of epinephrine which was effective in maintaining pupil size during cataract surgery, and to evaluate its influence on heart rate and blood pressure.…”

Investigation of the effects of intracameral carbachol on oxidative stress and apoptosis in rat corneas

“…Vaughn et al [7] found that carbachol had no effect on corneal thickness. Olson et al [16] showed that carbachol and commonly used intraocular medications had no significant effect on specular microscopy and the corneal endothelial in cats. Akiyama et al [17] investigated the effects of acetylcholine, carbachol, and mannitol on corneal endothelial function in rabbits.…”

Presumed herpetic endotheliitis following phacoemulsification surgery*

“…Pseudophakic bullous keratopathy occurring after cataract surgery is usually attributed to either pre‐existing low corneal endothelial cell counts 2 and diseases like Fuch’s endothelial dystrophy 3 or surgery‐induced insult to an otherwise normal corneal endothelium due to various factors 4–12 …”

Maintenance of Mydriasis with One Bolus of Epinephrine Injection During Phacoemulsification

“…However, systemic absorption of epinephrine during the operation may cause systemic side effects, such as elevated heart rate and blood pressure (4). Moreover, several studies reported that intracameral injection of high concentration epinephrine might lead to corneal injury (5)(6)(7). The purpose of the present study was to investigate the lowest concentration of epinephrine which was effective in maintaining pupil size during cataract surgery, and to evaluate its influence on heart rate and blood pressure.…”

Investigation of the effects of intracameral carbachol on oxidative stress and apoptosis in rat corneas

“…Vaughn et al [7] found that carbachol had no effect on corneal thickness. Olson et al [16] showed that carbachol and commonly used intraocular medications had no significant effect on specular microscopy and the corneal endothelial in cats. Akiyama et al [17] investigated the effects of acetylcholine, carbachol, and mannitol on corneal endothelial function in rabbits.…”

Presumed herpetic endotheliitis following phacoemulsification surgery*

“…Pseudophakic bullous keratopathy occurring after cataract surgery is usually attributed to either pre‐existing low corneal endothelial cell counts 2 and diseases like Fuch’s endothelial dystrophy 3 or surgery‐induced insult to an otherwise normal corneal endothelium due to various factors 4–12 …”

Maintenance of Mydriasis with One Bolus of Epinephrine Injection During Phacoemulsification

“…However, systemic absorption of epinephrine during the operation may cause systemic side effects, such as elevated heart rate and blood pressure (4). Moreover, several studies reported that intracameral injection of high concentration epinephrine might lead to corneal injury (5)(6)(7). The purpose of the present study was to investigate the lowest concentration of epinephrine which was effective in maintaining pupil size during cataract surgery, and to evaluate its influence on heart rate and blood pressure.…”