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Cited by 6 publications
(5 citation statements)
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“…More recently, a change in lipid packing imposed by the interaction of trehalose with the carbonyls was reported. 41 The issue of whether trehalose affects the lipid membrane area is also related to its ability to preserve biological structures. It has been shown that at full hydration, trehalose decreases the transition temperature between the lamellar and the hexagonal phase in dielaidoylphosphatidylethanolamine (DEPE) 42 and decreases the transition temperature between the interdigitated and the ripple phase in dihexadecylphosphatidylcholine (DHPC).…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…More recently, a change in lipid packing imposed by the interaction of trehalose with the carbonyls was reported. 41 The issue of whether trehalose affects the lipid membrane area is also related to its ability to preserve biological structures. It has been shown that at full hydration, trehalose decreases the transition temperature between the lamellar and the hexagonal phase in dielaidoylphosphatidylethanolamine (DEPE) 42 and decreases the transition temperature between the interdigitated and the ripple phase in dihexadecylphosphatidylcholine (DHPC).…”
Section: Discussionmentioning
confidence: 99%
“…This combination of effects explains why Merocyanine 540 partition is increased, denoting an exposure of hydrophobic regions, concomitant to an increase of 2 °C in the transition temperature. More recently, a change in lipid packing imposed by the interaction of trehalose with the carbonyls was reported …”
Section: Discussionmentioning
confidence: 99%
“…A prerequisite for an interaction is a transition of trehalose from the aqueous phase into the oil phase. Disalvo, Lairion, Martini, and Diaz (2002) reviewed that trehalose can insert into the lipid phase of membranes upon dehydration and a similar mechanism may have occurred during dehydration of the spray-dried emulsion.…”
Section: Development Of Lipid Oxidation Products Upon Storage Over Simentioning
confidence: 99%
“…Amphiphilic molecules, for example, generally partition into the membrane interface and cause lateral expansion and disordering of the membrane core. , This effect is particularly strong for charged amphiphiles such as fatty acids . Membrane partitioning for more polar compounds is controversial, but even molecules that are repelled from the interface affect the membrane properties indirectly through osmotic gradients close to the surface. , …”
Section: Introductionmentioning
confidence: 99%