Journal of Cell Biology volume 214, issue 3, P245-247 2016 DOI: 10.1083/jcb.201607023 View full text
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Clare E. Futter, Daniel F. Cutler

Abstract: Melanosome biogenesis requires successive waves of cargo delivery from endosomes to immature melanosomes, coupled with recycling of the trafficking machinery. Dennis et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201605090) report differential roles for BLOC-1 and BLOC-3 complexes in delivery and recycling of melanosomal biogenetic components, supplying directionality to melanosome maturation.