Comedogenic potential of the lipid extract of Pityrosporum ovale

Weary, P. E.

doi:10.1001/archderm.102.1.84

Cited by 11 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Why these hyperkeratotic changes occur however, is not clear. Pityrosporum, lipophilic yeast, has been thought to have comedogenic poten tial and be able to induce follicular hyperk eratosis (10,11). Some authors suggested that Propionibacterium acne may be important in inducing abnormal follicular keratinization in the pathogenesis of acne (12,13).…”

Section: Discussionmentioning

confidence: 99%

A Clinical, Microbiological, and Histopathologic Study of Trichostasis Spinulosa

Chung

Lee

Jang

et al. 1998

The Journal of Dermatology

View full text Add to dashboard Cite

Trichostasis spinulosa (TSS) is a relatively common follicular disorder that can occur on the face and trunk, especially in the interscapular area. Its cause remains unclear. We examined clinically 30 patients with TSS and follicular materials extracted from each patient were examined microscopically. Bacterial culture and skin biopsy were done in 12 and 10 patients, respectively. Periodic acid Schiff (PAS) and Brown-Brenn Gram stain were used for detection of pityrosporum (malassezia) and bacteria. The interscapular area (14/30), nose (8/30), and cheek (4/30) were common sites of TSS. Pityrosporum and bacteria in the extracted follicular material were found at the rates of 82.6% and 73.3%, respectively. In histologic examination, follicular hyperkeratosis and numerous vellus hairs enveloped within keratotic sheath were common features. Pityrosporum and bacteria were found at the rate of 70% in biopsied specimens on PAS and Brown-Brenn Gram stain. In bacterial culture, Propionibacterium acne was most commonly identified in 75% (9 out of 12 patients). Pityrosporum and bacteria, especially Propionibacterium acne, were commonly found in the extracted follicular material and biopsied specimens. Thus, they may be related to the induction of follicular hyperkeratosis with retention of vellus hairs, and we suggest that these microorganisms may be one of the possible etiologic factors of TSS.

show abstract

Section: Discussionmentioning

confidence: 99%