Combined psychotherapy plus antidepressants for panic disorder with or without agoraphobia

Abstract

Either combined therapy or psychotherapy alone may be chosen as first line treatment for panic disorder with or without agoraphobia, depending on patient preference.

Evidence-Based Brief Psychological Treatment for Emotional Disorders in Primary and Specialized Care: Study Protocol of a Randomized Controlled Trial

“…Although we think that psychological treatment (brief and conventional) will be more effective than pharmacological treatment, as suggested by previous results with patients with EDs (Heuzenroeder et al, 2004; Watts et al, 2015), we expect that “conventional psychological treatment plus pharmacological treatment” will be the most effective treatment. This findings will be compliant with other studies that indicate that the combined treatment is superior in efficacy to CBT and pharmacotherapy alone in both anxiety disorders (Furukawa et al, 2007; Van Apeldoorn et al, 2008) and depression (Keller et al, 2000; Pampallona et al, 2004).…”

Evidence-Based Brief Psychological Treatment for Emotional Disorders in Primary and Specialized Care: Study Protocol of a Randomized Controlled Trial

“…Although we think that psychological treatment (brief and conventional) will be more effective than pharmacological treatment, as suggested by previous results with patients with EDs (Heuzenroeder et al, 2004; Watts et al, 2015), we expect that “conventional psychological treatment plus pharmacological treatment” will be the most effective treatment. This findings will be compliant with other studies that indicate that the combined treatment is superior in efficacy to CBT and pharmacotherapy alone in both anxiety disorders (Furukawa et al, 2007; Van Apeldoorn et al, 2008) and depression (Keller et al, 2000; Pampallona et al, 2004).…”

Efficacy and Tolerability of Antidepressants for Treatment of Depression in Coronary Artery Disease: A Meta-Analysis

“…The tolerability data was summarized using the NNH, which was found to be 49. This is comparable to the NNH of 16 to 26 found in AD trials in other medical populations, [78][79][80][81] suggesting that tolerability in patients with CAD is similar. We were unable to identify any effect, either positive or negative, on cardiac parameters in these studies based on the adverse events reported.…”

Multiplicity of data in trial reports and the reliability of meta-analyses: empirical study

“…Furukawa and colleagues provided an example of a protocol with many possible intervention or control groups 8. The authors aimed to compare combined psychotherapy and pharmacotherapy with psychotherapy or pharmacotherapy alone.…”

“…The 19 eligible meta-analyses included 83 trials that contributed to our study. 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 Table 1 shows the characteristics of included reviews, which addressed various condition types: psychiatric (eight reviews), musculoskeletal (two), neurological (two), gynaecological (one), hepatological (one), respiratory (one), and other (four). We studied psychological interventions in 10 meta-analyses, pharmacological interventions in four, physical interventions in three, and other interventions in two (exercise and humidified air).…”

“…Furukawa and colleagues provided an example of a protocol with many possible intervention or control groups. 8 The authors aimed to compare combined psychotherapy and pharmacotherapy with psychotherapy or pharmacotherapy alone. They defined psychotherapy broadly, as “any other psychological approach.” 8 The pooled index SMD was based on seven trials, three of which had more than one possible intervention group.…”

Evidence-Based Brief Psychological Treatment for Emotional Disorders in Primary and Specialized Care: Study Protocol of a Randomized Controlled Trial

“…Although we think that psychological treatment (brief and conventional) will be more effective than pharmacological treatment, as suggested by previous results with patients with EDs (Heuzenroeder et al, 2004; Watts et al, 2015), we expect that “conventional psychological treatment plus pharmacological treatment” will be the most effective treatment. This findings will be compliant with other studies that indicate that the combined treatment is superior in efficacy to CBT and pharmacotherapy alone in both anxiety disorders (Furukawa et al, 2007; Van Apeldoorn et al, 2008) and depression (Keller et al, 2000; Pampallona et al, 2004).…”

Efficacy and Tolerability of Antidepressants for Treatment of Depression in Coronary Artery Disease: A Meta-Analysis

“…The tolerability data was summarized using the NNH, which was found to be 49. This is comparable to the NNH of 16 to 26 found in AD trials in other medical populations, [78][79][80][81] suggesting that tolerability in patients with CAD is similar. We were unable to identify any effect, either positive or negative, on cardiac parameters in these studies based on the adverse events reported.…”

Multiplicity of data in trial reports and the reliability of meta-analyses: empirical study

“…Furukawa and colleagues provided an example of a protocol with many possible intervention or control groups 8. The authors aimed to compare combined psychotherapy and pharmacotherapy with psychotherapy or pharmacotherapy alone.…”

“…The 19 eligible meta-analyses included 83 trials that contributed to our study. 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 Table 1 shows the characteristics of included reviews, which addressed various condition types: psychiatric (eight reviews), musculoskeletal (two), neurological (two), gynaecological (one), hepatological (one), respiratory (one), and other (four). We studied psychological interventions in 10 meta-analyses, pharmacological interventions in four, physical interventions in three, and other interventions in two (exercise and humidified air).…”

“…Furukawa and colleagues provided an example of a protocol with many possible intervention or control groups. 8 The authors aimed to compare combined psychotherapy and pharmacotherapy with psychotherapy or pharmacotherapy alone. They defined psychotherapy broadly, as “any other psychological approach.” 8 The pooled index SMD was based on seven trials, three of which had more than one possible intervention group.…”

Evidence-Based Brief Psychological Treatment for Emotional Disorders in Primary and Specialized Care: Study Protocol of a Randomized Controlled Trial

“…Although we think that psychological treatment (brief and conventional) will be more effective than pharmacological treatment, as suggested by previous results with patients with EDs (Heuzenroeder et al, 2004; Watts et al, 2015), we expect that “conventional psychological treatment plus pharmacological treatment” will be the most effective treatment. This findings will be compliant with other studies that indicate that the combined treatment is superior in efficacy to CBT and pharmacotherapy alone in both anxiety disorders (Furukawa et al, 2007; Van Apeldoorn et al, 2008) and depression (Keller et al, 2000; Pampallona et al, 2004).…”

Efficacy and Tolerability of Antidepressants for Treatment of Depression in Coronary Artery Disease: A Meta-Analysis

“…The tolerability data was summarized using the NNH, which was found to be 49. This is comparable to the NNH of 16 to 26 found in AD trials in other medical populations, [78][79][80][81] suggesting that tolerability in patients with CAD is similar. We were unable to identify any effect, either positive or negative, on cardiac parameters in these studies based on the adverse events reported.…”

Multiplicity of data in trial reports and the reliability of meta-analyses: empirical study

“…Furukawa and colleagues provided an example of a protocol with many possible intervention or control groups 8. The authors aimed to compare combined psychotherapy and pharmacotherapy with psychotherapy or pharmacotherapy alone.…”

“…The 19 eligible meta-analyses included 83 trials that contributed to our study. 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 Table 1 shows the characteristics of included reviews, which addressed various condition types: psychiatric (eight reviews), musculoskeletal (two), neurological (two), gynaecological (one), hepatological (one), respiratory (one), and other (four). We studied psychological interventions in 10 meta-analyses, pharmacological interventions in four, physical interventions in three, and other interventions in two (exercise and humidified air).…”

“…Furukawa and colleagues provided an example of a protocol with many possible intervention or control groups. 8 The authors aimed to compare combined psychotherapy and pharmacotherapy with psychotherapy or pharmacotherapy alone. They defined psychotherapy broadly, as “any other psychological approach.” 8 The pooled index SMD was based on seven trials, three of which had more than one possible intervention group.…”