Combined low-dose spinal-epidural anaesthesia versus single-shot spinal anaesthesia for elective caesarean delivery

Ghazi, Arif; Raja, Yogamany

doi:10.1016/j.ijoa.2006.07.003

Cited by 7 publications

(4 citation statements)

References 11 publications

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“…Recently, Ghazi and Raja [31] published a letter on their experience with low-dose CSE and concluded that the incidence of maternal hypotension and the need for vasopressors was reduced in women undergoing operative delivery.…”

Section: Introductionmentioning

confidence: 99%

Low-dose spinal anaesthesia for Caesarean section to prevent spinal-induced hypotension

Roofthooft

Velde

2008

Current Opinion in Anaesthesiology

124

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Section: Introductionmentioning

confidence: 99%

Low-dose spinal anaesthesia for Caesarean section to prevent spinal-induced hypotension

Roofthooft

Velde

2008

Current Opinion in Anaesthesiology

124

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“…8 Penelitian lain juga menyimpulkan bahwa insiden hipotensi ibu dan kebutuhan vasopressor berkurang pada wanita yang menjalani persalinan operatif. 9 Berdasarkan latar belakang tersebut, akan dibandingkan efek bupivakain dosis normal yaitu 12,5 mg dengan bupivakain dosis rendah yaitu 5 mg yang ditambahkan fentanyl 50 mg.…”

Section: Pendahuluanunclassified

Perbandingan Efektivitas Anestesi Spinal dengan Bupivacain 12,5 Mg dan Bupivacain 5 Mg yang ditambah Fentanyl 50 Mcg pada Seksio Sesarea

Indradata

Purnomo²,

Thamrin³

et al. 2021

JAOI

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Latar Belakang: Anestesi spinal mempunyai efek samping berupa hipotensi dan mual muntah. Tujuan: penelitian ini adalah membandingkan efek anestesi spinal bupivacain dosis normal 12,5 mg dan bupivacain dosis rendah 5 mg dengan fentanyl 50 mg pada seksio sesarea terhadap perubahan hemodinamik, ketinggian blok, onset, durasi dan efek samping. Subjek dan Metode: Penelitian double blind randomized control trial pada 36 pasien yang memenuhi kriteria. Pasien dibagi menjadi dua kelompok, yang masing-masing terdiri 18 pasien, kelompok 1 dilakukan anestesi spinal dengan bupivacain hiperbarik 5 mg ditambah adjuvan fentanyl 50 mcg, sedangkan kelompok 2 diberikan bupivacain hiperbarik 12,5 mg. Penilaian meliputi saat mula kerja blokade sensorik, mula kerja blokade motorik, durasi, tekanan darah, laju nadi, dan saturasi oksigen, lama kerja dan efek samping. Data hasil penelitian diuji secara statistik dengan uji chi-square. Hasil: Terdapat perbedaan signifikan pada onset dan durasi blokade sensorik dan motorik, bupivacain 12,5 mg lebih baik dibandingkan bupivacain 5 mg + fentanyl 50 mcg (p<0.05). Tidak ada perbedaan signifikan pada perubahan tanda vital dan efek samping (p>0.05). Simpulan: Bupivacain 12,5 mg menghasilkan onset lebih cepat dan durasi lebih lama dibandingkan bupivacain 5 mg + fentanil 50 mcg pada anestesi spinal untuk seksio sesarea Comparison of The Effectiveness Spinal Anesthesia with Bupivacaine 12,5 Mg and Bupivacaine 5 Mg added Fentanyl 50 Mcg in Caesarean Section Abstract Background: Spinal anesthesia has side effects such as hypotension and nausea and vomiting. Objective: The aim of this study was to compare the effects of spinal anesthesia with normal doses of 12,5 mg of bupivacaine and 5 mg of low-dose bupivacaine with fentanyl 50 mg in the cesarean section on hemodynamic changes, block height, onset, duration, and side effects. Subjects and Methods: Double-blind randomized control trial in 36 patients who met the criteria. Patients were divided into two groups, each consisting of 18 patients, group 1 underwent spinal anesthesia with 5 mg of hyperbaric bupivacaine plus 50 mcg of fentanyl adjuvant, while group 2 was given 12,5 mg of hyperbaric bupivacaine. Assessments include the initiation of sensory block action, onset of motor block action, duration, blood pressure, pulse rate, and oxygen saturation, duration of action, and side effects. The research data were statistically tested with the chi-square test. Results: There were significant differences in the onset and duration of sensory and motor blockade, bupivacaine 12,5 mg was better than bupivacaine 5 mg + fentanyl 50 mcg (p <0.05). There was no significant difference in changes in vital signs and side effects (p> 0.05). Conclusion: Bupivacaine 12,5 mg resulted in a faster onset and longer duration than bupivacaine 5 mg + fentanyl 50 mcg in spinal anesthesia for cesarean section.

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“…6 Others have suggested that the orientation of the orifice does not influence the spread of hyperbaric solutions. 7,8 Two of these studies were in non-obstetric patients, so extrapolation to obstetrics may not be valid. James et al demonstrated a more rapid onset sensory block with the orifice of a 24-gauge Sprotte needle directed cephalad using isobaric 0.5% bupivacaine, but no difference in the maximum sensory block height, incidence of hypotension or maternal satisfaction.…”

Section: Successful Spinal Blockade In a Parturient With Myotonia Conmentioning

confidence: 99%

Successful spinal blockade in a parturient with myotonia congenita

Farrow

Carling

2007

International Journal of Obstetric Anesthesia

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Combined low-dose spinal-epidural anaesthesia versus single-shot spinal anaesthesia for elective caesarean delivery

Cited by 7 publications

References 11 publications

Low-dose spinal anaesthesia for Caesarean section to prevent spinal-induced hypotension

Low-dose spinal anaesthesia for Caesarean section to prevent spinal-induced hypotension

Perbandingan Efektivitas Anestesi Spinal dengan Bupivacain 12,5 Mg dan Bupivacain 5 Mg yang ditambah Fentanyl 50 Mcg pada Seksio Sesarea

Successful spinal blockade in a parturient with myotonia congenita

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