Combined Exposure to Mixture of Chemicals. An Impossible Challenge?

Degiorgi, François; Adam, Olivier; Gregorio, Crini

doi:10.5772/13469

Cited by 2 publications

(2 citation statements)

References 55 publications

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“…Finally, some other pollutants that are not directly toxic to human beings or whose environmental concentrations in the biota are not high have also been the object of several investigations. This is because they can modify environmental characteristics and bring about major environmental damage (Pierre-Marie et al 2011). Thus, researchers have produced considerable knowledge that will assist the management of emerging contaminants.…”

Section: Future Perspectivesmentioning

confidence: 99%

“…Thus, researchers have produced considerable knowledge that will assist the management of emerging contaminants. Unfortunately, people, animals, and the environment have actually been exposed to multiple chemicals from a variety of sources at once, while current risk assessment is most often carried out on one chemical substance only, at low doses (EFSA 2013;Pierre-Marie et al 2011).…”

Section: Future Perspectivesmentioning

confidence: 99%

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A perspective on the potential risks of emerging contaminants to human and environmental health

Pereira

Souza

Bernardes

et al. 2015

Environ Sci Pollut Res

202

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Technological, agricultural, and medical advances have improved the lifestyle of humankind. However, these advances have caused new problems that affect the environment and future generations. Emerging contaminants display properties such as low degradation potential and environmental persistence. In addition, most contaminants are lipophilic, which culminates in high bioaccumulation. The disposal of pharmaceuticals and personal care products into the environment underlies microbial and bacterial resistance. Plasticizers change several characteristics of industrialized materials, such as flexibility, but they are potentially carcinogenic and disrupt the endocrine system. Pesticides prevent the propagation of numerous kinds of pests; nevertheless, they exert neurotoxic and mutagenic effects, and they impact the environment negatively. Addition of flame retardants to a number of materials prevents flame propagation; however, after their release into the environment, these chemicals may bioaccumulate in organisms and disrupt the endocrine system, too. Surfactants can change the surface and interfacial properties of liquids, but their presence in the environment can interfere with countless enzymes and can even impair the endocrine system of various organisms and induce the feminization of species. Hence, gaining knowledge about emerging contaminants is increasingly important to minimize future damage and enable proper monitoring of each class of compounds in the environment which will help to improve legislation on this matter.

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Section: Future Perspectivesmentioning

confidence: 99%

Section: Future Perspectivesmentioning

confidence: 99%