Combined effects of bisphenol A and cadmium on growth and nitrate assimilation of soybean seedling roots

Sun, Zilong; Wang, Lihong; Wang, Qingqing; Zhou, Qing; Huang, Xiaohua

doi:10.1002/etc.2647

Cited by 5 publications

(2 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although BPA is expected to be degraded quickly, it is ubiquitous in some natural environments owing to its continuous input. Recent studies have shown that BPA has inevitably influenced the balance of the ecosystem, having seriously threatened environmental safety . Among the soil ecosystems, nematodes are the most abundant metazoan in soil with high environmental relevance, playing a key role in decomposition, nutrient cycling, and maintenance of environmental quality.…”

Section: Introductionmentioning

confidence: 99%

Ecotoxicological evaluation of low‐concentration bisphenol A exposure on the soil nematode Caenorhabditis elegans and intrinsic mechanisms of stress response in vivo

Zhou

Yang

et al. 2016

Enviro Toxic and Chemistry

View full text Add to dashboard Cite

As a representative species of nematodes, Caenorhabditis elegans is an attractive animal model for evaluating ecotoxicological effects and intrinsic mechanisms of the stress response in vivo. To acquire a better knowledge of environmental effects of bisphenol A (BPA), ecotoxicological evaluations were conducted using C. elegans on the physiological (growth, locomotion behaviors, and reproduction), biochemical (lipofuscin accumulation, reactive oxygen species production, and cell apoptosis), and molecular (stress-related gene expression) responses. Nematodes were exposed to BPA (0.001-10 µM) in 2 assay systems (L4 larvae for 24 h and L1 larvae for 72 h). Exposure to BPA could significantly (p< 0.05) alter body length, locomotion behaviors, brood size, cell apoptosis, and selected stress-related gene expression. At the physiological level, BPA exerted adverse effects on nematodes at the microgram per liter level in both assay systems, with head thrashes as the most sensitive endpoint. At the biochemical level, apoptosis degree showed increases at concentrations above 0.1 µM in both assay systems. At the molecular level, BPA induced increases in selected stress-related gene expression, even at the lowest tested concentration. In addition, BPA-induced cell apoptosis was suggested as a potential mode of action, resulting in adverse physiological effects. Therefore, BPA exposure was speculated to impose developmental, reproductive, and neurobehavioral toxicities on C. elegans and caused variations of stress-related gene expression. Environ Toxicol Chem 2016;35:2041-2047. © 2016 SETAC.

show abstract

Section: Introductionmentioning

confidence: 99%

Ecotoxicological evaluation of low‐concentration bisphenol A exposure on the soil nematode Caenorhabditis elegans and intrinsic mechanisms of stress response in vivo

Zhou

Yang

et al. 2016

Enviro Toxic and Chemistry

View full text Add to dashboard Cite

show abstract

“…Current studies have indicated that bisphenols affect ecosystem balance and threaten environmental safety (Ike et al ; Ji et al ; René and Watson ; Hu et al ; Sun et al ), but studies on the comparative toxicity of bisphenol analogs are limited. In the soil ecosystem, nematodes are the most abundant metazoan, with a high response to perturbations; they play a key role in nutrient cycling, decomposition, and environmental quality maintenance.…”

Section: Introductionmentioning

confidence: 99%

Ecotoxicity of bisphenol S to Caenorhabditis elegans by prolonged exposure in comparison with bisphenol A

Zhou

2018

Enviro Toxic and Chemistry

View full text Add to dashboard Cite

Because of increasing concerns about its toxic effects, bisphenol A (BPA) has been gradually replaced in industrial applications by analogs such as bisphenol S (BPS). Few comparative toxicity evaluations of bisphenol analogs have been done. In the present study, 72-h exposure in L1 larvae of the model animal Caenorhabditis elegans was used to evaluate low-concentration BPS toxicity. Multiple indicators at the physiological, biochemical, and molecular levels were tested. At the physiological level, BPS exposure resulted in significantly negative effects at treatments >1 µM, with head thrash being the most sensitive endpoint. At the biochemical level, BPS exposure induced no significant oxidative stress, but significantly increased apoptosis at 1 µM. At the molecular level, BPS exposure induced small but significant variations in most stress-related gene expressions at all doses. In addition, the transgenic nematode TJ375 cell line with the green fluorescent protein-based reporter hsp-16.2 was used to determine stress responses; it was found that TJ375 was not sensitive to BPS exposure. Compared with the effects of BPA shown in our previous 2016 study, the overall results showed that BPS was less noxious to C. elegans than BPA. These toxicity data for BPS could provide a foundation to evaluate the comparative toxicity of BPA alternatives. Environ Toxicol Chem 2018;37:2560-2565. © 2018 SETAC.

show abstract

Bisphenol A Affects Soybean Growth by Inhibiting Root Nodules and Germination

Wang

Huang²,

Tanida³

et al. 2023

Water Air Soil Pollut

View full text Add to dashboard Cite

Combined effects of bisphenol A and cadmium on growth and nitrate assimilation of soybean seedling roots

Cited by 5 publications

References 37 publications

Ecotoxicological evaluation of low‐concentration bisphenol A exposure on the soil nematode Caenorhabditis elegans and intrinsic mechanisms of stress response in vivo

Ecotoxicological evaluation of low‐concentration bisphenol A exposure on the soil nematode Caenorhabditis elegans and intrinsic mechanisms of stress response in vivo

Ecotoxicity of bisphenol S to Caenorhabditis elegans by prolonged exposure in comparison with bisphenol A

Bisphenol A Affects Soybean Growth by Inhibiting Root Nodules and Germination

Contact Info

Product

Resources

About