Combined Effect of Vitamin C and E Dose on Type 2 Diabetes Patients

Prajapat, Rajneesh; Bhattacharya, Ijen; Jakhalia, Anupam

doi:10.13189/adm.2017.050201

Cited by 4 publications

(2 citation statements)

References 28 publications

(32 reference statements)

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“…The results showed no significant difference between vitamin C intake and HbA1c. This supports the study conducted by Dakhale et al (2011); Hamed et al, (2016) and Prajapat et al (2017). Donin et al (2015) revealed the risk of type 2 diabetes was more determined by systemic vitamin C levels, rather than vitamin C intake.…”

Section: The Relationship Between Vitamin C Intake and Hba1csupporting

confidence: 85%

Association between Carbohydrate, Vitamin C, Vitamin E, and HBA1C Level

2019

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Background:Diabetes is now a disease that is a major concern both globally and regionally and is the leading cause of death in most countries. HbA1c levels are used to measure longterm glucose levels in patients with type 1 and 2 Diabetes Mellitus (DM). Restrictions on carbohydrate diets have the greatest effect on decreasing blood glucose levels. Nutritional interventions with the provision of vitamin C and vitamin E can reduce inflammation and oxidative stress as a strategy to prevent the occurrence of DM. The purpose of this study was to determine the relationship of carbohydrate intake, vitamin C and vitamin E with HbA1c levels.

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Section: The Relationship Between Vitamin C Intake and Hba1csupporting

confidence: 85%

Association between Carbohydrate, Vitamin C, Vitamin E, and HBA1C Level

2019

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“…Diabetes mellitus is metabolic epidemic that occur due to ineffective secretion of insulin from pancreas [1,2] and the possibly the worldwide number of diabetic patient will be rise up to 439 million by 2030 [3,4]. Vitamin E supplementation could improve glycemic control in diabetes patients [5,6].Vitamin C supplementation is effective in prevention of non-enzymatic glycosylation of proteins [7] and it also serves as therapeutic agent for diseases that protects body from damage caused by free radicals [8].…”

Section: Introductionmentioning

confidence: 99%

Effect of Vitamin E and C Supplementation on Oxidative Stress in Diabetic Patients

Prajapat¹,

Bhattacharya²

2017

adm

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Background: Diabetes is a metabolic epidemic that causes vascular complications. The presence of oxidative stress in diabetes patients and the preventive role of vitamins therapy have been reported by many researchers. Vitamins supplementation improves antioxidant defense system in diabetes patients. Aim: To study the effect of vitamin E and C supplementation on oxidative stress in diabetes patients. Methods: Subjects enrolled in the study received 500 mg of both vitamin C and vitamin E daily twice for 4 months under medical supervision. Fasting blood glucose, MDA, catalase, SOD and nitric oxide were determined. Serum vitamin E and plasma vitamin C were also measured. Statistical analysis was performed using SPSS 12.0. Numerical normally distributed and categorical data were compared using independent t-test. Data were presented as means ± SD. Results: After supplementation with vitamin E and C in diabetic patients, a signify decrease in FBS, MDA levels and increase in serum nitrite, erythrocyte SOD, blood catalase, vitamin E and vitamin C levels were observed. A negative correlation between MDA and vitamins was observed. Conclusion: Vitamin E and C supplementation is useful for the treatment of oxidative stress related complications in diabetes patients. Prescribed medicines contain active ingredients that may cause effect on the patients in terms of side-effects. Controlled vitamin therapy for prolonged period may not cause any side-effects, as well as play effective role for the management of type 2 diabetic related oxidative stress.

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Type 2 Diabetes Mellitus And Vitamin C

Ishrat¹,

Hoor²,

Jaffri³

2019

J. Bahria Uni. Med. Dent. Coll.

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Type 2 diabetes mellitus (DM) is a chronic disease which deteriorates the quality of life with time. Type 2 DM accounts for more than 90% cases of diabetes mellitus as compared to other types of this disease. There is significant oxidative stress in type 2 DM which plays an important role in the pathogenesis of disease. In order to combat this oxidative stress antioxidant supplements have to be added as add on therapy along with treatment of type 2 DM. Vitamin C is the safest antioxidant which plays significant role in diminishing the oxidative stress. The vitamin C supplementation have good control of FBS and HbA1c and therefore helps in achieving better glycemic control along with prevention of lipid abnormalities.

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Combined Effect of Vitamin C and E Dose on Type 2 Diabetes Patients

Cited by 4 publications

References 28 publications

Association between Carbohydrate, Vitamin C, Vitamin E, and HBA1C Level

Association between Carbohydrate, Vitamin C, Vitamin E, and HBA1C Level

Effect of Vitamin E and C Supplementation on Oxidative Stress in Diabetic Patients

Type 2 Diabetes Mellitus And Vitamin C

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