Combined Directed Metalation – Suzuki-Miyaura Cross Coupling Strategies. Synthesis of Isomeric Chromenopyridinones and Related Annulated Analogues

The Versatile and Strategic O-Carbamate Directed Metalation Group in the Synthesis of Aromatic Molecules: An Update

“…The chiral binaphthol carbaldehyde 373a is an example of a useful building block. An efficient ruthenium(II)-catalyzed C−H hydroxylation of ArOAms was developed for the facile synthesis of catechol (374) and pyrogallol derivatives (375) from readily accessible phenols (Scheme 90). 369 This method has excellent regio-and chemoselectivity, good functional group tolerance and high yield, and offers a new route for the construction of some biologically important molecules.…”

“…Similar compounds ( 393 , 394 , 396 , 398 , and 399 ) have been prepared by Snieckus et al using D re M/A o F rearrangement/lactonization sequence (examples shown in Scheme a–c).…”

“…Synthesis of Fused Heterocycles with a [1,4]Oxathiin Ring (346, 347) Using DoM, DreM-Rearrangement, and Cyclization a Adapted from ref 364. Copyright 2005 The Japan Institute of Heterocyclic Chemistry.Similar compounds(393, 394, 396, 398, and 399) have been prepared by Snieckus et al375 using DreM/AoF rearrangement/ lactonization sequence (examples shown in Scheme 94a−c).…”