Combination Treatment With Acyclovir and Prednisone for Bell Palsy

Bell’s palsy in Mosul

“…There is an agreement that most cases of Bell's palsy are caused by reactivations of latent herpes virus type 1 (HSV-1) infections of geniculate ganglia of facial nerves (11,12,(18)(19)(20)(21)(22) . These reactivations lead to inflammation, swelling, compression, and ultimately, dysfunction of affected facial nerves.…”

Ramsay-Hunt syndrome: a case report

“…It represents 7% of all peripheral facial paralysis and recovery rates are lower in this group [4,5]. Early treatment with a combination of acyclovir and prednisone is reported to be effective [6][7][8].…”

Ramsay Hunt syndrome

“…Early treatment with a combination of acyclovir and prednisone is reported to be effective to treat Ramsay Hunt syndrome [2526]. Antiviral agents such as acyclovir and famciclovir improve acute pain and recovery of lesions from herpes zoster and prevent the occurrence of postherpetic neuralgia [127].…”

“…Additionally, early treatment can improve hearing loss. Acyclovir–prednisone was found to prevent degeneration of nerves with nerve excitability testing and enhance the recovery rate of facial nerve palsy [2526]. There is no statistical difference in the treatment with oral or intravenous acyclovir [18].…”