Combination therapy for psoriasis. Psoralens plus long-wave ultraviolet radiation with betamethasone valerate

Hanke, C. William

doi:10.1001/archderm.115.9.1074

Cited by 19 publications

(6 citation statements)

References 6 publications

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“…These were combination therapy studies with conflicting results in which one arm each investigated PUVA with placebo. From the other studies, 17 studies were assigned a grade of evidence of B 114,239–253 and one a grade of evidence of C 254 . This results in a level of evidence of 2.…”

mentioning

confidence: 99%

European S3‐Guidelines on the systemic treatment of psoriasis vulgaris

Pathirana¹,

Ormerod²,

Saïag³

et al. 2009

Acad Dermatol Venereol

617

892

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mentioning

confidence: 99%

European S3‐Guidelines on the systemic treatment of psoriasis vulgaris

Pathirana¹,

Ormerod²,

Saïag³

et al. 2009

Acad Dermatol Venereol

617

892

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“…Combined therapies appear to be the most effective of all in clearing recalcitrant widespread and severe psoriasis [1]. One of the most frequent of the combination is PUVA topical steroid [8]. In contrast with PUVA, topical steroids appear to show a more rapid rate of clearing and a smaller total UVA dose when used in combination [9].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Puvasol and Puvasol With Topical Betamethasone Dipropionate Plus Salicylic Acid Lotion in the Treatment of Scalp Psoriasis

Ramasastry

Dhaka

1999

Medical Journal Armed Forces India

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The efficacy and safety of betamethsone dipropionate 0.05% with salicylic acid 2% scalp lotion was evaluated in 60 patients with moderate to severe scalp psoriasis. Out of 120 patients with scalp psoriasis 60 patients received PUVASOL alone and 60 patients received PUVASOL alongwith lotion 0.05% betamethasone dipropionate with 2% salicylic acid scalp application for 3 weeks. The erythema, induration, scales and pruritus steadily improved in patients throughout the 3 weeks treatment course with betamethasone dipropionate with salicylic acid scalp application. At the end of therapy 84.3% of those patients receiving PUVASOL and betamethasone dipropionate-salicylic acid combination had 75% improvement of their scalp psoriasis versus 34.9% of those patients using PUVASOL alone. Complete clearing of the scalp was seen in 35% patients receiving therapy with topical betamethasone-salicylic acid and 11.6% with PUVASOL alone. Local side effects were primarily burning and stinging in 5 (83%) cases treated with topical betamethasone salicylic acid scalp application and 1 (1.6%) receiving PUVASOL alone. Combined therapy with PUVASOL and topical betamethasone dispropionate 0.05% with salicyclic acid 2% application appears to be safe and an effective treatment for scalp psoriasis.

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“…Yet, another study on the combination of betamethasone with oral PUVA showed a synergistic effect. In all treated patients, skin lesions healed after an average of 13.6 days compared with an average of 20.25 days in the oral PUVA group [221] (EG B).…”

Section: Phototherapymentioning

confidence: 99%

S3 – Guidelines on the treatment of psoriasis vulgaris (English version). Update

Nast

Boehncke

Mrowietz

et al. 2012

J Deutsche Derma Gesell

250

247

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Psoriasis vulgaris is a common and often chronic inflammatory skin disease. The incidence of psoriasis in Western industrialized countries ranges from 1.5% to 2%. Patients afflicted with severe psoriasis vulgaris may experience a significant reduction in quality of life. Despite the large variety of treatment options available, surveys have shown that patients still do not received optimal treatments. To optimize the treatment of psoriasis in Germany, the Deutsche Dermatologi sche Gesellschaft (DDG) and the Berufsverband Deutscher Dermatologen (BVDD) have initiated a project to develop evidence-based guidelines for the management of psoriasis. They were first published in 2006 and updated in 2011. The Guidelines focus on induction therapy in cases of mild, moderate and severe plaque-type psoriasis in adults including systemic therapy, UV therapy and topical therapies. The therapeutic recommendations were developed based on the results of a systematic literature search and were finalized during a consensus meeting using structured consensus methods (nominal group process).

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Combination therapy for psoriasis. Psoralens plus long-wave ultraviolet radiation with betamethasone valerate

Cited by 19 publications

References 6 publications

European S3‐Guidelines on the systemic treatment of psoriasis vulgaris

European S3‐Guidelines on the systemic treatment of psoriasis vulgaris

Evaluation of Puvasol and Puvasol With Topical Betamethasone Dipropionate Plus Salicylic Acid Lotion in the Treatment of Scalp Psoriasis

S3 – Guidelines on the treatment of psoriasis vulgaris (English version). Update

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