Collision tumor of apocrine carcinoma and squamous carcinoma occurring in the ear

Lorusso, Giovanni D.; Sarma, Deba P.; Fazekas-May, Mary; Roth, James; Sarwar, Syeda F.

doi:10.1016/j.amjoto.2004.01.009

Cited by 6 publications

(2 citation statements)

References 8 publications

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“…12 Cases of AC in areas usually lacking apocrine glands such as the wrist have also been reported. 4 Clinically, these lesions are typically slow growing, painless, colorless or red, cystic or firm nodules. 4 Clinically, these lesions are typically slow growing, painless, colorless or red, cystic or firm nodules.…”

Section: Discussionmentioning

confidence: 99%

Anal Apocrine Carcinoma

Hall

Florell²,

Sklow³

et al. 2012

The American Journal of Dermatopathology

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Apocrine carcinoma (AC) is an extremely rare skin appendage tumor, which is located at lower dermal and subcutaneous tissue. We report a case of an anal AC arising from an apocrine adenoma in the anal region, which is only the second case reported in this region. A 71-year-old male presented to clinic with soreness in the anal region for 6 weeks. An excisional biopsy was performed. Histologically, the lesion was poorly circumscribed, infiltrative, and was composed of small to medium sized glands extending to the surgical margins. There were centrally dilated large glands with duct-like openings into the mucosal surface. The larger central glands contain periodic acid-Schiff-positive eosinophilic acellular secretions. At the periphery, there were smaller glands with significant cytologic atypia and numerous mitoses. A diagnosis of AC was made making it the second case report of this very rare malignancy in this region. Although ACs usually do not have a fatal outcome, there have been case reports of distant metastases and even death from this disease, making histologic distinction of this malignancy from a benign apocrine adenoma important. Wide local excision is typically the treatment of choice, although Mohs micrographic surgery has also been used with similar success.

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Section: Discussionmentioning

confidence: 99%

Anal Apocrine Carcinoma

Hall

Florell²,

Sklow³

et al. 2012

The American Journal of Dermatopathology

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“…During 6 months of follow-up, no relapse of the lesions was observed.Cutaneous collision tumors with SCC are uncommon. Reports described combinations of SCC with epidermal cysts(Veenstra, Choudhry, Krajenta, & Eide, 2016), melanoma(Scruggs, Rensvold, Parekh, & Butler, 2011), and apocrine carcinoma(Lorusso, Sarma, Fazekas-May, Roth, & Sarwar, 2004). A collision of SCC with trichilemmal cysts is exceptionally rare.…”

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confidence: 99%