Collagenase Activity of Dog Pancreatic Juice

Digestive System

“…Ziffren & Hosie (217) found a collagenase in canine pancreatic juice, and it remains to be compared with pankrin.…”

Transformation of Collagen to "Elastin" in Dermal Collagens with Varying Sensitivity towards Collagenase

“…The importance of the reactivity of collagen to collagenase has recently been shown by Ziffren and Hosie (1955), who demonstrated collagenase activity in canine pancreatic juice. Previous work (Keech, 1954b) suggested the presence of some substance capable of altering collagen in human dermis of all age groups.…”

Electron Microscopic Study of the Effect of Prolonged Heat and Ultra-Violet Light on Human Dermis from Different Age Groups

“…In the living body, enzyme systems also play a part, of course, in both the breakdown and the synthesis of tissue structures. For example, collagenase-activity has recently been demonstrated in dog pancreatic juice (Ziffren and Hosie, 1955). This is the first time that collagenase has been demonstrated in mammals.…”