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citations
Cited by 54 publications
(68 citation statements)
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References 4 publications
(6 reference statements)
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“…Our results suggest that coinfection with other respiratory pathogens could be detected in saliva samples. In the present study, coinfection was uncommon among patients with COVID-19; although the rate was consistent with that reported in previous studies reporting SARS-CoV-2 coinfection rates in NPS samples [28], it was lower than the rate of viral coinfection reported among patients with SARS-CoV-2 using respiratory virome characterization [29]. Determining the coinfection rate and its consequent clinical impacts on COVID-19 is critical, particularly where therapeutic interventions are available for some coinfecting agents such as influenza virus.…”
Section: Discussionsupporting
confidence: 93%
“…Our results suggest that coinfection with other respiratory pathogens could be detected in saliva samples. In the present study, coinfection was uncommon among patients with COVID-19; although the rate was consistent with that reported in previous studies reporting SARS-CoV-2 coinfection rates in NPS samples [28], it was lower than the rate of viral coinfection reported among patients with SARS-CoV-2 using respiratory virome characterization [29]. Determining the coinfection rate and its consequent clinical impacts on COVID-19 is critical, particularly where therapeutic interventions are available for some coinfecting agents such as influenza virus.…”
Section: Discussionsupporting
confidence: 93%
“…In parallel, the provincial public health laboratory maintained broad, syndromic nucleic acid testing for additional viral and bacterial pathogens, rapidly amassing data on 18 respiratory pathogens from 52,285 respiratory specimens, including SARS-CoV-2. As a result, to our knowledge this study represents the largest singleyear eCoV study [2][3][4][5] and by far the largest eCoV study during the COVID-19 pandemic [7][8][9][10][11][12][13]. This broad testing approach helps to address a pivotal diagnostic gap amidst the emergence of a novel pathogen: co-infection and possible cross-reactivity with other pathogens that can cause similar clinical presentations.…”
Section: Discussionmentioning
confidence: 96%
“…Since SARS-CoV-2 emerged, there has been little research on the concurrent circulation of these other respiratory viruses, which had been the subject of broad surveillance in the years prior [2][3][4][5]: only a handful of case reports have described co-infections between SARS-CoV-2 and other respiratory viruses able to cause similar symptoms [6][7][8][9][10][11][12][13]. With unprecedented demand on clinical diagnostics, re-prioritized surveillance is one of many ways that laboratories have had to prioritize and adapt throughout this pandemic [14][15][16][17].…”
Section: Introductionmentioning
confidence: 99%
“…Richardson et al [ 16 ] reported that the rate of co-infection with other pathogens was 2.1% among 5700 COVID-19 patients in New York City. Hazra et al [ 17 ] also reported that at least 1 respiratory pathogen combined with SARS-CoV-2 occurred in 3.3% of detected specimens. These studies suggested that there are relatively great differences in the number and types of co-infecting respiratory pathogens in COVID-19 patients across countries and regions.…”
Section: Discussionmentioning
confidence: 99%