Cohort Profile: The Copenhagen Child Cohort Study (CCC2000)

Olsen, Else Marie; Rask, Charlotte Ulrikka; Elberling, Hanne; Jeppesen, Pia; Clemmensen, Lars; Munkholm, Anja; Li, Xiao Qiang; Hansen, Mathias Hvidtfelt; Rimvall, Martin Køster; Linneberg, Allan; Munch, Inger Christine; Larsen, Michael; Jørgensen, Torben; Skovgaard, Anne Mette

doi:10.1093/ije/dyz256

Cited by 24 publications

(37 citation statements)

References 34 publications

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“…The cohort constitutes nearly 10% of children born in Denmark that year and has been found to be representative of Danish children concerning perinatal and sociodemographic characteristics at baseline, except for a higher proportion of immigrant families (Skovgaard et al, 2005). Updated analyses at age 16 years found the cohort to be comparable with national data concerning parental education and the children's mean grade from elementary school graduation (Olsen et al, 2019). The cohort has been followed since birth by assessments at important developmental ages and ongoing follow‐up in the Danish national registries, using the unique civil registration number assigned to all citizens in Denmark at birth.…”

Section: Methodsmentioning

confidence: 57%

“…The limitations of the study include potential attrition bias, as the participants differed from the original representative birth cohort concerning sex and socio‐economic characteristics (Olsen et al, 2019). Participants in the 16‐years‐follow‐up were more often from families with higher maternal education, higher income, without hospital diagnosed psychopathology, and less often of immigrant background.…”

Section: Discussionmentioning

confidence: 99%

“…At age 16 years, all eligible cohort members (5,938 of 6,070 adolescents alive) were invited to participate in a follow‐up assessment. A total of 2,509 (response rate 42.3%) completed the eating section of a comprehensive web‐based questionnaire on mental health (at mean age 16.5 years; SD 4.2 months), and 1,511 (response rate 25.4%) also participated in a subsequent face‐to‐face examination (Olsen et al, 2019). Compared to the non‐participating adolescents, the participants included more girls and fewer adolescents with psychiatric disorders or from low‐income families (Olsen et al, 2019).…”

Section: Methodsmentioning

confidence: 99%

“…Finally, we included self‐rated impact of food and weight related thoughts and behaviors on daily life. We constructed this item specifically for the 16‐year follow‐up of CCC2000 inspired by a similar impact question from the validated Body Distress Syndrome checklist (Budtz‐Lilly et al, 2015; Olsen et al, 2019). Body mass index (BMI) was calculated from weight and height (kg/m 2 ) and categorized into weight‐status categories of thin, normal weight, overweight and obesity using the age and sex‐specific International Obesity Task Force cut‐offs (Cole & Lobstein, 2012).…”

Section: Methodsmentioning

confidence: 99%

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Self‐reported symptoms of binge‐eating disorder among adolescents in a community‐based Danish cohort—A study of prevalence, correlates, and impact

Olsen

Koch

Skovgaard

et al. 2020

Intl J Eating Disorders

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Objective Binge‐eating disorder (BED) was established as a diagnosis in 2013 with the DSM‐5 and has been included in the ICD‐11 in 2018. In adulthood, BED is prevalent and correlated with somatic and mental health problems. Less is known about BED in adolescence, although this age period could represent a window of opportunity for early intervention. This study aimed to investigate the 1‐year prevalence, correlates, and impact of BED symptoms in a community sample of adolescents. Method We included 1,404 girls and 1,105 boys from the 16‐years‐follow‐up of the Copenhagen Child Cohort study, CCC2000. The adolescents self‐reported on BED symptoms, weight‐status, body perception, mental health problems, and self‐rated impact of food and weight‐related thoughts and behaviors. Information about socio‐economic factors and hospital diagnosed psychiatric disorders were obtained from national registries. Results A total of 8.5% reported weekly overeating with loss of control (10.9% of girls, 4.8% of boys), and 2.6% (3.6% of girls, 1.2% of boys) reported symptoms consistent with BED according to the DSM‐5. Regardless of sex, BED was correlated with concurrent overweight, body‐dissatisfaction, low self‐esteem, and mental health problems, especially emotional, but also with problems of behavior, inattention, and peer‐relations, and with high self‐rated impact on everyday life. Immigrant background and lower socio‐economy were potential risk factors for BED in boys in this sample. Discussion BED was prevalent and correlated with mental health problems and overall impact among adolescents in this community sample, indicating the need for clinical attention and intervention towards binge‐eating disorder in the adolescent period.

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Section: Methodsmentioning

confidence: 57%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

See 2 more Smart Citations

Self‐reported symptoms of binge‐eating disorder among adolescents in a community‐based Danish cohort—A study of prevalence, correlates, and impact

Olsen

Koch

Skovgaard

et al. 2020

Intl J Eating Disorders

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“…No information regarding participant's ethnicity were available. However, the cohort was found to be representative of the Danish population [37]. In 2017, the Danish population consisted of 69,260 17years-olds of which 90% were white Caucasians who originates from Denmark (88%) or other Western Countries (2%).…”

Section: Discussionmentioning

confidence: 99%

Axial length change and its relationship with baseline choroidal thickness – a five-year longitudinal study in Danish adolescents: the CCC2000 eye study

Hansen

Kessel

et al. 2020

BMC Ophthalmol

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Background: Myopic eyes are longer than nonmyopic eyes and have thinner choroids. The purpose of present study was to investigate whether a thinner subfoveal choroid at 11 years of age predicted axial eye elongation and myopia during adolescence. Methods: Longitudinal, population-based observational study. Axial length was measured using an interferometric device and choroidal thickness was measured by spectral-domain optical coherence tomography. Myopia was defined as non-cycloplegic subjective spherical equivalent refraction ≤ − 0.50 diopters. Results: Right eyes of 714 children (317 boys) were examined at age (median (IQR)) 11.5 (0.6) years and 16.6 (0.3) years during which axial length (median (IQR)) increased by 243 (202) μm in eyes without myopia (n = 630) at baseline compared with 454 (549) μm in eyes with myopia (n = 84) at baseline, p < 0.0001. A thicker baseline subfoveal choroid was associated with increased five-year axial elongation after adjustment for baseline axial length in nonmyopic eyes (β = 27 μm/100 μm, 95%CI 6 to 48, p = 0.011) but not in myopic eyes (p = 0.34). Subfoveal choroidal thickness at 11 years of age did not predict incident myopia at 16 years of age (p = 0.11). Longer baseline axial length was associated with greater five-year axial elongation in both myopic (β = 196 μm/mm, 95%CI 127 to 265, p < 0.0001) and nonmyopic eyes (β = 28 μm/mm, 95%CI 7 to 49, p = 0.0085) and the odds for incident myopia increased with 1.57 (95%CI 1.18 to 2.09, p = 0.0020) per mm longer axial length at baseline. Conclusion: A thin subfoveal choroid at age 11 years did not predict axial eye elongation and incident myopia from age 11 to 16 years. A longer eye at age 11 years was associated with greater subsequent axial eye elongation and with increased risk of incident myopia at age 16 years.

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Comparison of prevalence and mental health problems across symptom frequency of self‐reported symptoms of binge‐eating disorder in a community sample of adolescents

Andersen

Strandberg‐Larsen

Skovgaard

et al. 2023

Intl J Eating Disorders

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ObjectiveBinge‐eating disorder (BED) and subthreshold BED (SBED) are prevalent in adults and associated with mental health problems including depression, non‐suicidal self‐injury, lower quality of life, and suicidality. There is solid evidence that binge‐eating behaviors are also prevalent in adolescence, but knowledge about mental health in community adolescents with BED of different frequency thresholds is more limited. We aimed to investigate the prevalence and mental health problems associated with SBED of low frequency and/or limited duration compared with BED in a Danish community sample of adolescents.MethodsWe included 2509 adolescents who completed the online survey of the 16–17‐year follow‐up of the Copenhagen Child Cohort (CCC2000), including items on BED symptoms approximating the Diagnostic and Statistical Manual of Mental Disorders (DSM‐5) criteria, and items on mental health and quality of life.ResultsThe 1‐year prevalence of SBED was 2.7% (95% confidence interval [CI]: 2.0%–3.3%) with a male:female ratio of 1:3.7; comparable to previous findings on BED in the same sample. SBED was also comparable to BED concerning cross‐sectional associations with overall mental health problems, lower health‐related quality of life, depressive symptoms, and suicidal ideation, whereas no associations were seen with non‐suicidal self‐injury after Holm–Bonferroni correction. In both groups, thoughts and behaviors concerning food and weight interfered significantly with daily life.DiscussionSBED and BED were equally prevalent in this adolescent community sample, and similarly associated with indicators of poor mental health. The findings indicate that community adolescents reporting symptoms approximating clinical criteria of BED need intervention irrespectively of symptom frequency or duration.Public SignificanceThis study adds knowledge to the field by comparing BED of low frequency and/or limited duration (“subthreshold BED,” SBED) with full‐syndrome BED in adolescents and showing that SBED in adolescence is both prevalent and associated with poor mental health to a similar extent as that of BED. Findings indicate that self‐reported symptoms according to clinical criteria of SBED and BED alike constitute a public health problem and point to youngsters in need of intervention.

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Cohort Profile: The Copenhagen Child Cohort Study (CCC2000)

Cited by 24 publications

References 34 publications

Self‐reported symptoms of binge‐eating disorder among adolescents in a community‐based Danish cohort—A study of prevalence, correlates, and impact

Self‐reported symptoms of binge‐eating disorder among adolescents in a community‐based Danish cohort—A study of prevalence, correlates, and impact

Axial length change and its relationship with baseline choroidal thickness – a five-year longitudinal study in Danish adolescents: the CCC2000 eye study

Comparison of prevalence and mental health problems across symptom frequency of self‐reported symptoms of binge‐eating disorder in a community sample of adolescents

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