2020
DOI: 10.3390/ijms21249510
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Abstract: Aging is a multifactorial process accompanied by loss of cell function. Science has been looking for factors responsible for aging for many years. However, despite identifying a number of possible causes, the definite reason for aging has been elusive so far. One of the factors contributing to aging is oxygen free radicals. In this context, beneficial effects of coffee on various organisms, including humans, were investigated, although the results are far from unequivocal. In our research, we used the budding … Show more

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Cited by 22 publications
(11 citation statements)
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“…The metabolic activity of yeast cells was evaluated using the FUN-1 probe according to the manufacturer’s instructions (Molecular Probes, Illkirch, France) with previously described modifications [ 52 ].…”
Section: Methodsmentioning
confidence: 99%
“…The metabolic activity of yeast cells was evaluated using the FUN-1 probe according to the manufacturer’s instructions (Molecular Probes, Illkirch, France) with previously described modifications [ 52 ].…”
Section: Methodsmentioning
confidence: 99%
“…This gives possibilities to follow the overall metabolic switch during the lifespan and study certain factors that control this. Recently there has been a huge amount of research on yeast CLS aimed at using these unicellular eukaryotes as a model for testing the antiaging activities of different compounds [ 12 , 13 ] and for studying the fine molecular mechanisms that underlie the process, including research on cellular metabolism and telomere biology in regard to aging [ 14 , 15 ]. Moreover, personal perspectives also appeared highlighting the importance of the yeast CLS research as a compelling stipulation for providing really deep insights on the process in higher eukaryotes [ 16 ].…”
Section: Introductionmentioning
confidence: 99%
“…Coffee has many benefits for the body. It not only protects cells from damage [1] and cardiovascular diseases [2] but also reduces the risk of cancer [3]; therefore, coffee is an essential commodity and a popular beverage [4]. Currently, it is produced in approximately 60 tropical and subtropical countries and is exported as an agricultural product [5].…”
Section: Introductionmentioning
confidence: 99%