Coexistent Meige's Syndrome and Myasthenia Gravis

Blepharospasm with elevated anti-acetylcholine receptor antibody titer

“…Our major finding of this study was that the level of anti-AChR Abs in BSP patients was higher than the levels in patients with HFS and healthy controls. Anti-AChR antibodies are typically IgG1 or IgG3, with a high affinity for AChR, and a dissociation constant of 10 -10 M anti-AChR Abs are specific for patients with MG 11 ; and MG and BSP coexist in some patients 6,12,13 , suggesting a strong association between BSP and MG. The common features for both MG and BSP include predominant eyelid involvement, ptosis with unequal palpebral fissures, rest benefit, diurnal change, aggravation from reading and fatigue, excessive blinking, and photophobia.…”

Blepharospasm with elevated anti-acetylcholine receptor antibody titer

“…Our major finding of this study was that the level of anti-AChR Abs in BSP patients was higher than the levels in patients with HFS and healthy controls. Anti-AChR antibodies are typically IgG1 or IgG3, with a high affinity for AChR, and a dissociation constant of 10 -10 M anti-AChR Abs are specific for patients with MG 11 ; and MG and BSP coexist in some patients 6,12,13 , suggesting a strong association between BSP and MG. The common features for both MG and BSP include predominant eyelid involvement, ptosis with unequal palpebral fissures, rest benefit, diurnal change, aggravation from reading and fatigue, excessive blinking, and photophobia.…”

Blepharospasm and autoimmune diseases

“…We also reported five patients with the combination of MG and cranial dystonia (4). Besides these patients with coexistent MG and cranial dystonia, we are aware of another patient, a 13-year-old Chinese girl with 10 years of MG and 4 years of diurnal dystonia (5).…”

Electronystagmographic Analysis of Optokinetic Nystagmus for the Evaluation of Ocular Symptoms in Myasthenia Gravis

“…Weakness of external ocular muscles may be the first sign of the generalized MG. The diagnosis of ocular MG is not always simple (2,3). Ocular symptoms have a diurnal rhythm.…”

Blepharospasm with elevated anti-acetylcholine receptor antibody titer

“…Our major finding of this study was that the level of anti-AChR Abs in BSP patients was higher than the levels in patients with HFS and healthy controls. Anti-AChR antibodies are typically IgG1 or IgG3, with a high affinity for AChR, and a dissociation constant of 10 -10 M anti-AChR Abs are specific for patients with MG 11 ; and MG and BSP coexist in some patients 6,12,13 , suggesting a strong association between BSP and MG. The common features for both MG and BSP include predominant eyelid involvement, ptosis with unequal palpebral fissures, rest benefit, diurnal change, aggravation from reading and fatigue, excessive blinking, and photophobia.…”

Blepharospasm and autoimmune diseases

“…We also reported five patients with the combination of MG and cranial dystonia (4). Besides these patients with coexistent MG and cranial dystonia, we are aware of another patient, a 13-year-old Chinese girl with 10 years of MG and 4 years of diurnal dystonia (5).…”

Electronystagmographic Analysis of Optokinetic Nystagmus for the Evaluation of Ocular Symptoms in Myasthenia Gravis

“…Weakness of external ocular muscles may be the first sign of the generalized MG. The diagnosis of ocular MG is not always simple (2,3). Ocular symptoms have a diurnal rhythm.…”

Blepharospasm with elevated anti-acetylcholine receptor antibody titer

“…Our major finding of this study was that the level of anti-AChR Abs in BSP patients was higher than the levels in patients with HFS and healthy controls. Anti-AChR antibodies are typically IgG1 or IgG3, with a high affinity for AChR, and a dissociation constant of 10 -10 M anti-AChR Abs are specific for patients with MG 11 ; and MG and BSP coexist in some patients 6,12,13 , suggesting a strong association between BSP and MG. The common features for both MG and BSP include predominant eyelid involvement, ptosis with unequal palpebral fissures, rest benefit, diurnal change, aggravation from reading and fatigue, excessive blinking, and photophobia.…”

Blepharospasm and autoimmune diseases

“…We also reported five patients with the combination of MG and cranial dystonia (4). Besides these patients with coexistent MG and cranial dystonia, we are aware of another patient, a 13-year-old Chinese girl with 10 years of MG and 4 years of diurnal dystonia (5).…”

Electronystagmographic Analysis of Optokinetic Nystagmus for the Evaluation of Ocular Symptoms in Myasthenia Gravis

“…Weakness of external ocular muscles may be the first sign of the generalized MG. The diagnosis of ocular MG is not always simple (2,3). Ocular symptoms have a diurnal rhythm.…”