Coagulase-Negative Staphylococcal Infections

Characterization of coagulase-negative staphylococci isolated from hospital indoor air and a comparative analysis between airborne and inpatient isolates of Staphylococcus epidermidis

“…Thus, the high rates of multiresistance detected suggest that these airborne CoNS are most probably hospital-derived isolates. Additionally, the species distribution of the airborne CoNS was similar to that reported previously for clinical isolates associated with health-care-associated infections (Viale & Stefani, 2006;Rogers et al, 2009 It was evident from our data that patient isolates of S. epidermidis showed a significantly higher ability to accumulate biofilms than airborne isolates. Despite this, the percentage of biofilm producers among the airborne CoNS was also very high (96.3 %), and about half of the airborne S. epidermidis isolates also showed a superior ability to accumulate biofilms.…”

“…Premature babies are especially susceptible (Cheung & Otto, 2010). Among CoNS, Staphylococcus epidermidis is the most common species isolated from clinical sources (National Nosocomial Infections Surveillance System, 2004;Gales et al, 2009;Rogers et al, 2009). It has been suggested that the pathogenic potential of CoNS is due mainly to their ability to form/ accumulate ica-dependent and -independent biofilms on the surfaces of indwelling medical devices (O'Gara, 2007;Rogers et al, 2009;Cheung & Otto, 2010).…”

“…Among CoNS, Staphylococcus epidermidis is the most common species isolated from clinical sources (National Nosocomial Infections Surveillance System, 2004;Gales et al, 2009;Rogers et al, 2009). It has been suggested that the pathogenic potential of CoNS is due mainly to their ability to form/ accumulate ica-dependent and -independent biofilms on the surfaces of indwelling medical devices (O'Gara, 2007;Rogers et al, 2009;Cheung & Otto, 2010). However, besides ica, other genes have been associated with biofilm formation/accumulation in S. epidermidis including aap, atlE and hld, encoding accumulation adhesion protein, a major autolysin of S. epidermidis and agr d-toxin, respectively (Otto, 2009).…”

Prospective study of bacteremia rate after elective band ligation and sclerotherapy with cyanoacrylate for esophageal varices in patients with advanced liver disease

“…Despite some reports of Staphylococcus hominis strains causing nosocomial bloodstream infection (15) and the recognition that coagulase-negative staphylococcus can cause clinically significant infections (18) , these bacteria might be regarded as contaminants. This suggestion is based on the fact that coagulase-negative staphylococcus are one of the most frequent causes of blood culture contamination (18) , and because these patients presented no clinically significant alterations. The other case, a different microorganism was isolated after third BL session.…”

Identification of Coagulase-Negative Staphylococci by the Bruker MALDI-TOF Biotyper Compared To the Vitek 2 and MIS Gas Liquid Chromatography

“…Forty different species are now recognized to be of significance in human disease [1][2][3]. CNS are associated with many different infections and among others causes infections of foreign bodies like prosthetic joints [4] and they are considered to be a major cause of line associated bacteremia in hospitalized patients [5,6]. Coagulasenegative Staphylococci are well-known to cause other significant infections; acting as opportunistic pathogens in surgical site infections, colonization of vascular access devices or as a urinary tract pathogen such as Staphylococcus saprophyticus [4,5].…”