Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome

Abstract

Analysis 2.1. Comparison 2 Antioestrogen versus antioestrogen, Outcome 1 Live birth rate (per woman

Effect Of Adding Vitamin D Supplement to Clomiphene Citrate For Induction Of Ovulation In Cases Of Overweight PCOS Women

“…Our results revealed that group I has higher incidence of induction and successful pregnancy but in a non significant manner. This similar to Brown et al 26 who reported in their study that clomiphene citratre has no difference on getting pregnancy which was in agreement with our results. Also, Rasheed et al 27 revealed in their study that addition of vitamin D to clomifine citrate significantly improve the ovulation rate which run in lines with our results but in our results the difference was not significant.…”

Effect Of Adding Vitamin D Supplement to Clomiphene Citrate For Induction Of Ovulation In Cases Of Overweight PCOS Women

“…Our results revealed that group I has higher incidence of induction and successful pregnancy but in a non significant manner. This similar to Brown et al 26 who reported in their study that clomiphene citratre has no difference on getting pregnancy which was in agreement with our results. Also, Rasheed et al 27 revealed in their study that addition of vitamin D to clomifine citrate significantly improve the ovulation rate which run in lines with our results but in our results the difference was not significant.…”

Effect of clomiphene citrate on endometrial thickness, ovulation, pregnancy and live birth in anovulatory women: systematic review and meta‐analysis

“…On the other hand, Misso et al 7 found comparable ovulation rates between CC and letrozole (RR, 0.94; 95% CI, 0.82-1.07; I 2 = 0%) while the pregnancy rate was higher in the letrozole group, albeit there was no evidence of significant difference (RR, 1.53; 95% CI, 0.91-2.58; I 2 = 50%). Brown et al 6 found no evidence of a difference between CC and tamoxifen in ovulation and pregnancy rates while finding higher rates of both when adding dexamethasone to CC compared with CC alone, and these results are also in agreement with our study results. In women with unexplained subfertility undergoing intrauterine insemination, a recent meta-analysis reported no difference in EMT between CC and letrozole (WMD, −0.84; 95% CI, −1.97 to 0.28) 68 .…”

Endometrial scratch for infertile polycystic ovary syndrome (PCOS) women undergoing laparoscopic ovarian drilling: a randomized controlled trial

“…This is consistent with the reported 70-80% ovulation rate in the literature [8]. Women who failed to have spontaneous ovulation following LOD were subjected to ovulation induction [28,29]. We used clomiphene citrate, tamoxifen, letrozole, and exogenous gonadotropins to induce ovulation in these women.…”

Effect Of Adding Vitamin D Supplement to Clomiphene Citrate For Induction Of Ovulation In Cases Of Overweight PCOS Women

“…Our results revealed that group I has higher incidence of induction and successful pregnancy but in a non significant manner. This similar to Brown et al 26 who reported in their study that clomiphene citratre has no difference on getting pregnancy which was in agreement with our results. Also, Rasheed et al 27 revealed in their study that addition of vitamin D to clomifine citrate significantly improve the ovulation rate which run in lines with our results but in our results the difference was not significant.…”

Effect of clomiphene citrate on endometrial thickness, ovulation, pregnancy and live birth in anovulatory women: systematic review and meta‐analysis

“…On the other hand, Misso et al 7 found comparable ovulation rates between CC and letrozole (RR, 0.94; 95% CI, 0.82-1.07; I 2 = 0%) while the pregnancy rate was higher in the letrozole group, albeit there was no evidence of significant difference (RR, 1.53; 95% CI, 0.91-2.58; I 2 = 50%). Brown et al 6 found no evidence of a difference between CC and tamoxifen in ovulation and pregnancy rates while finding higher rates of both when adding dexamethasone to CC compared with CC alone, and these results are also in agreement with our study results. In women with unexplained subfertility undergoing intrauterine insemination, a recent meta-analysis reported no difference in EMT between CC and letrozole (WMD, −0.84; 95% CI, −1.97 to 0.28) 68 .…”

Endometrial scratch for infertile polycystic ovary syndrome (PCOS) women undergoing laparoscopic ovarian drilling: a randomized controlled trial

“…This is consistent with the reported 70-80% ovulation rate in the literature [8]. Women who failed to have spontaneous ovulation following LOD were subjected to ovulation induction [28,29]. We used clomiphene citrate, tamoxifen, letrozole, and exogenous gonadotropins to induce ovulation in these women.…”

Effect Of Adding Vitamin D Supplement to Clomiphene Citrate For Induction Of Ovulation In Cases Of Overweight PCOS Women

“…Our results revealed that group I has higher incidence of induction and successful pregnancy but in a non significant manner. This similar to Brown et al 26 who reported in their study that clomiphene citratre has no difference on getting pregnancy which was in agreement with our results. Also, Rasheed et al 27 revealed in their study that addition of vitamin D to clomifine citrate significantly improve the ovulation rate which run in lines with our results but in our results the difference was not significant.…”

Effect of clomiphene citrate on endometrial thickness, ovulation, pregnancy and live birth in anovulatory women: systematic review and meta‐analysis

“…On the other hand, Misso et al 7 found comparable ovulation rates between CC and letrozole (RR, 0.94; 95% CI, 0.82-1.07; I 2 = 0%) while the pregnancy rate was higher in the letrozole group, albeit there was no evidence of significant difference (RR, 1.53; 95% CI, 0.91-2.58; I 2 = 50%). Brown et al 6 found no evidence of a difference between CC and tamoxifen in ovulation and pregnancy rates while finding higher rates of both when adding dexamethasone to CC compared with CC alone, and these results are also in agreement with our study results. In women with unexplained subfertility undergoing intrauterine insemination, a recent meta-analysis reported no difference in EMT between CC and letrozole (WMD, −0.84; 95% CI, −1.97 to 0.28) 68 .…”

Endometrial scratch for infertile polycystic ovary syndrome (PCOS) women undergoing laparoscopic ovarian drilling: a randomized controlled trial

“…This is consistent with the reported 70-80% ovulation rate in the literature [8]. Women who failed to have spontaneous ovulation following LOD were subjected to ovulation induction [28,29]. We used clomiphene citrate, tamoxifen, letrozole, and exogenous gonadotropins to induce ovulation in these women.…”