Clinicopathologic and molecular correlates to neoadjuvant chemotherapy‐induced pathologic response in breast angiosarcoma
Hsin‐Yi Chang,
Josephine K. Dermawan,
Maria Gabriela Kuba
et al.
Abstract:Both primary and secondary breast angiosarcoma (AS) are characterized by multifocal presentation and aggressive behavior. Despite multimodality therapy, local and distant relapse rates remain high. Therefore, neoadjuvant chemotherapy (NACT) is employed to improve the R0 resection rates and survival, but its benefits remain controversial. Herein, we investigate pathologic and molecular correlates to NACT‐induced histologic response in a group of 29 breast AS, 4 primary and 25 radiation‐associated (RA). The two … Show more
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