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Cited by 3 publications
(6 citation statements)
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“…30 The expression of UCA1 is elevated in patients with ARDS, and knockdown of UCA1 can reduce lung injury through inhibiting inflammatory response, reflecting that UCA1 is involved in ALI. 31 In the current research, the expression of UCA1 was positively related to the LUS scores in patients with ALI, reflecting that UCA1 is associated with the severity of lung injury. In addition, LUS score could distinguish ALI patients with death prognosis from survival ones.…”
Section: Itemssupporting
confidence: 52%
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“…30 The expression of UCA1 is elevated in patients with ARDS, and knockdown of UCA1 can reduce lung injury through inhibiting inflammatory response, reflecting that UCA1 is involved in ALI. 31 In the current research, the expression of UCA1 was positively related to the LUS scores in patients with ALI, reflecting that UCA1 is associated with the severity of lung injury. In addition, LUS score could distinguish ALI patients with death prognosis from survival ones.…”
Section: Itemssupporting
confidence: 52%
“…In the SiO 2 dust‐treated mouse silicosis model, the expression of UCA1 is correlated to the presence of silicosis 6 . As documented by Chen et al, UCA1 is highly expressed in patients with acute RDS and has the clinical possibility of differentiating these kinds of patients 7 . Collectively, UCA1 may be an abnormally expressed lncRNA in ALI, and its screening significance catches our attention.…”
Section: Introductionmentioning
confidence: 90%
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“…In addition, different experimental models have their own distinct limitations [ 33 ], and treatments may produce disparate inflammatory effects, thus influencing UCA1 function. Nevertheless, since UCA1 has been implicated in several inflammatory diseases such as acute respiratory distress syndrome [ 19 ], sepsis [ 34 ], pneumonia [ 20 ], and acute ischemic stroke [ 35 ], we can surmise that UCA1 plays a pro-inflammatory role in psoriasis.…”
Section: Discussionmentioning
confidence: 99%
“…Recent studies show that UCA1 also has a regulatory role in inflammatory responses. For example, increased level of UCA1 in the blood is associated with an increased risk of acute respiratory distress syndrome in patients undergoing cardiopulmonary bypass [ 19 ], and UCA1 overexpression can worsen acute septic pneumonia by upregulating the expression of EZH2 and suppressing HOXA1 [ 20 ]. We previously found that the UCA1 is a functional regulator in skin cells, and is highly expressed in keratinocytes [ 21 ].…”
Section: Introductionmentioning
confidence: 99%