Clinical Spectrum and Long-term Outcome of 183 Cases of Ebstein's Anomaly, Experience of Mexican Population

Herrera-Bello, Héctor; Ávila-Vanzzini, Nydia; Fritche-Salazar, Juan Francisco; Kuri-Alfaro, Jorge; Gaxiola-Macías, Manuel; Cossio-Aranda, Jorge

doi:10.1016/j.arcmed.2020.03.008

Cited by 2 publications

(4 citation statements)

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“… 1 25 Clinical presentation after neonatal period has a more favourable outcome than cases diagnosed in earlier life. 26 Subjects growing up to adulthood exhibit less severe anatomical abnormalities and, due to high right chambers compliance to volume overload, are usually asymptomatic for a long time. 25 27 28 Mean age at diagnosis is around 14 years among children and 20–35 years in adults.…”

Section: From Bench To Bedsidementioning

confidence: 99%

“…Right-to-left shunt may lead to chronic hypoxia and exertional cyanosis, while rest cyanosis is more common during infancy. 26 Cerebrovascular embolic events, as assessed in around 8%–10% of cases, are attributable to either paradoxical embolization or atrial fibrillation occurrence. 26 28 Endocarditis is rare and favoured by device implantation or surgery.…”

Section: From Bench To Bedsidementioning

confidence: 99%

“… 26 Cerebrovascular embolic events, as assessed in around 8%–10% of cases, are attributable to either paradoxical embolization or atrial fibrillation occurrence. 26 28 Endocarditis is rare and favoured by device implantation or surgery. 26 29 Figure 5 illustrates distinctive EA symptoms and their physiological substrates.…”

Section: From Bench To Bedsidementioning

confidence: 99%

“… 26 28 Endocarditis is rare and favoured by device implantation or surgery. 26 29 Figure 5 illustrates distinctive EA symptoms and their physiological substrates.…”

Section: From Bench To Bedsidementioning

confidence: 99%

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Ebstein’s anomaly in children and adults: multidisciplinary insights into imaging and therapy

Pasqualin¹,

Boccellino²,

Chessa³

et al. 2023

Heart

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Although survival has significantly improved in the last four decades, the diagnosis of Ebstein’s anomaly is still associated with a 20-fold increased risk of mortality, which generally drops after neonatal period and increases subtly thereafter. With increasing age of presentation, appropriate timing of intervention is challenged by a wide spectrum of disease and paucity of data on patient-tailored interventional strategies. The present review sought to shed light on the wide grey zone of post-neonatal Ebstein’s manifestations, highlighting current gaps and achievements in knowledge for adequate risk assessment and appropriate therapeutic strategy.A ‘wait-and-see’ approach has been adopted in many circumstances, though its efficacy is now questioned by the awareness that Ebstein’s anomaly is not a benign disease, even when asymptomatic. Moreover, older age at intervention showed a negative impact on post-surgical outcome.In order to tackle the extreme heterogeneity of Ebstein’s anomaly, this review displays the multimodality imaging assessment necessary for a proper anatomical classification and the multidisciplinary approach needed for a comprehensive risk stratification and monitoring strategy. Currently available predictors of clinical outcome are summarised for both operated and unoperated patients, with the aim of supporting the decisional process on the choice of appropriate therapy and optimal timing for intervention.

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Section: From Bench To Bedsidementioning

confidence: 99%

Section: From Bench To Bedsidementioning

confidence: 99%

Section: From Bench To Bedsidementioning

confidence: 99%

“… 26 28 Endocarditis is rare and favoured by device implantation or surgery. 26 29 Figure 5 illustrates distinctive EA symptoms and their physiological substrates.…”

Section: From Bench To Bedsidementioning

confidence: 99%

See 2 more Smart Citations