Clinical significance of T2*-weighted gradient-echo MRI to monitor graft maturation over one year after anatomic double-bundle anterior cruciate ligament reconstruction: A comparative study with proton density-weighted MRI

Hakozaki, Akihiro; Niki, Yasuo; Enomoto, Hiroyuki; Toyama, Yoshiaki; Suda, Yasunori

doi:10.1016/j.knee.2014.11.004

Cited by 19 publications

(35 citation statements)

References 33 publications

(43 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…SI measurements with MRI has been used in other clinical studies for evaluation of the ACL graft and maturation after ACL reconstruction compared to clinical and functional outcomes [ 9 , 12 , 17 , 18 ]. However, none of these studies used SI to compare the TT technique with the AMP technique.…”

Section: Discussionmentioning

confidence: 99%

“…Also, some of these studies examined the feasibility of T2*WI. The T2*WI sequence was more strongly associated with clinical outcomes (KT-2000 arthrometer) [ 12 ]. Biercevicz et al showed also that volume and grayscale values from T2*WI MRI scans are predictive of the healing ligament [ 9 , 18 ].…”

Section: Discussionmentioning

confidence: 99%

“…Hakozaki et al assessed the SIR of the double-bundle ACL graft 12 months after ACL reconstruction with the AMP technique [ 12 ]. On MRI, the SIR of the graft 12 months postoperative was measured of 61 patients.…”

Section: Methodsmentioning

confidence: 99%

“…MRI assessment with PDWI fails to correlate SI with actual graft function. A more promising technique is T2*-weighted gradient-echo MRI imaging which has been reported as a useful imaging modality to assess graft integrity [ 12 ]. The signal intensity ratio (SIR) can be calculated by: …”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

MRI signal intensity of anterior cruciate ligament graft after transtibial versus anteromedial portal technique (TRANSIG): design of a randomized controlled clinical trial

Ruiter¹,

Brouwer²,

Meys³

et al. 2016

BMC Musculoskelet Disord

View full text Add to dashboard Cite

BackgroundThere are two primary surgical techniques to reconstruct the anterior cruciate ligament (ACL), transtibial (TT) technique and anteromedial portal (AMP) technique. Currently, there is no consensus which surgical technique elicits the best clinical and functional outcomes. MRI-derived measures of the signal intensity (SI) of the ACL graft have been described as an independent predictor of graft properties. The purpose of this study is to compare the MRI derived SI measurements of the ACL graft one year after ACL reconstruction, in order to compare the outcomes of both the AMP and TT ACL reconstruction technique.Methods/designThirty-six patients will be included in a randomized controlled trial. Patients who are admitted for primary unilateral ACL reconstruction will be included in the study. Exclusion criteria are a history of previous surgery on the ipsilateral knee, re-rupture of the ipsilateral ACL graft, associated ligamentous injuries or meniscal tear of the ipsilateral knee, unhealthy contralateral knee, contra-indications for MRI and a preference for one of the two surgical techniques and/or orthopaedic surgeon. Primary outcome is MRI Signal intensity ratio (SIR) of the ACL graft. Secondary outcome measures are the International Knee Documentation Committee (IKDC) Knee Examination Form,the Knee injury and Osteoarthritis Outcome Scores (KOOS) and the Anterior Cruciate Ligament OsteoArthritis Score (ACLOAS). Differences between MRI SIR assessment with the current MRI protocol (proton density weighted imaging protocol) and the additional T2*-weighted gradient-echo protocol will be assessed.DiscussionThere is no consensus regarding the TT or AMP ACL reconstruction technique. SI measurements with MRI have been used in other clinical studies for evaluation of the ACL graft and maturation after ACL reconstruction compared to clinical and functional outcomes. This randomized controlled trial has been designed to compare the TT technique with the AMP technique with the use of MRI SI of the graft after ACL reconstruction.Trial registrationNetherlands Trial Registry NTR5410 (registered on August 24, 2015).

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

MRI signal intensity of anterior cruciate ligament graft after transtibial versus anteromedial portal technique (TRANSIG): design of a randomized controlled clinical trial

Ruiter¹,

Brouwer²,

Meys³

et al. 2016

BMC Musculoskelet Disord

View full text Add to dashboard Cite

show abstract

“…Following anatomical DB-t ACL-r, abnormalities seen on T2 Ã -weighted sequence were more strongly associated with clinical knee instability than the routinely used PD-w sequence. 62 It seems that increasing values in T2 Ã signals from 6 to 12 months postoperatively are able to detect a poorly functioning graft. This may have an implication in choosing the optimal timing for a return to sporting activities; a delayed return to preinjury sports activities should be considered for patients with increased SI on T2 Ã at 12 months postoperatively, until evidence is obtained of decreasing trends.…”

Section: Normal Postoperative Mri Findings Anterior Cruciate Ligamentmentioning

confidence: 99%

Current Concepts on MRI Evaluation of Postoperative Knee Ligaments

Tsifountoudis

Karantanas

2016

Semin Musculoskelet Radiol

View full text Add to dashboard Cite

The growing number of patients undergoing arthroscopy or surgery of the knee for ligamentous injuries has led to a greater need for postoperative imaging because of poor outcome, recurrent symptoms, or a new injury. MRI is the most important imaging method when evaluating the postoperative knee. Radiologists should be familiar with the particular reconstruction technique applied to each examinee, know the spectrum of normal postoperative findings, recognize those findings that may be related to symptoms of failed reconstruction, as well as those lesions that are irrelevant to the previous surgery yet responsible for the new clinical symptoms. In view of the continually evolving surgical techniques, this review presents the current concepts of MRI evaluation of the postoperative knee ligaments based on recent literature reports.

show abstract

Diffusion tensor imaging of the anterior cruciate ligament following primary repair with internal bracing: A longitudinal study

Dyck

Froeling

Heusdens

et al. 2020

Journal Orthopaedic Research

View full text Add to dashboard Cite

Diffusion tensor imaging (DTI) provides information about tissue microstructure and its degree of organization by quantifying water diffusion. We aimed to monitor longitudinal changes in DTI parameters (fractional isotropy, FA; mean diffusivity, MD; axial diffusivity, AD; radial diffusivity, RD) of the anterior cruciate ligament (ACL) following primary repair with internal bracing (IBLA). Fourteen patients undergoing IBLA were enrolled prospectively and scheduled for clinical follow‐up, including instrumented laxity testing, and DTI at 3, 6, 12, and 24 months postoperatively. DTI was also performed in seven healthy subjects. Fiber tractography was used for 3D segmentation of the whole ACL volume, from which median DTI parameters were calculated. The posterior cruciate ligament (PCL) served as a control. Longitudinal DTI changes were assessed using a linear mixed model, and repeated measures correlations were calculated between DTI parameters and clinical laxity tests. At follow‐up, thirteen patients had a stable knee and one patient sustained an ACL rerupture after 12 months postoperatively. The ACL repair showed a significant decrease of FA within the first 12 months after surgery, followed by stable FA values thereafter, while ACL diffusivities decreased over time returning towards normal values at 24 months postoperatively. For PCL there were no significant DTI changes over time. There was a significant correlation between ACL FA and laxity tests (r = −0.42, P = .017). This study has shown the potential of DTI to longitudinally monitor diffusion changes in the ACL following IBLA. The DTI findings suggest that healing of the ACL repair is incomplete at 24 months postoperatively.

show abstract

Clinical significance of T2*-weighted gradient-echo MRI to monitor graft maturation over one year after anatomic double-bundle anterior cruciate ligament reconstruction: A comparative study with proton density-weighted MRI

Cited by 19 publications

References 33 publications

MRI signal intensity of anterior cruciate ligament graft after transtibial versus anteromedial portal technique (TRANSIG): design of a randomized controlled clinical trial

MRI signal intensity of anterior cruciate ligament graft after transtibial versus anteromedial portal technique (TRANSIG): design of a randomized controlled clinical trial

Current Concepts on MRI Evaluation of Postoperative Knee Ligaments

Diffusion tensor imaging of the anterior cruciate ligament following primary repair with internal bracing: A longitudinal study

Contact Info

Product

Resources

About