volume 8, issue 9, P2204-2221 2016
DOI: 10.18632/aging.101037
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Jun Chi, Qing Yang, Xiao-Feng Xie, Xian-Zi Yang, Mei-Yin Zhang, Hui-Yun Wang, Guo-Liang Xu

Abstract: Tripartite motif-containing 24 (TRIM24), a member of the transcription intermediary factor 1 family, is defined as a co-regulator with several nuclear receptors, such as RARα. TRIM24 has been reported to be involved in many cancers. In this study, we aimed to investigate the expression pattern and prognostic significance of TRIM24 and its relationship with RARα in esophageal squamous cell cancer (ESCC). Both mRNA and protein expression levels of TRIM24 were found to be significantly decreased in ESCC, as judge…

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