Clinical results of biologic prosthesis: A systematic review and meta-analysis of comparative studies

Wilasrusmee, Chumpon; Siribumrungwong, Boonying; Horsirimanont, Suthas; Poprom, Napaphat; Jirasiritham, Jakrapan; Thakkinstian, Ammarin

doi:10.1016/j.amsu.2017.01.018

Cited by 9 publications

(6 citation statements)

References 17 publications

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“…In these kind of situations, alternative graft usage should be considered. Although ePTFE has been the most preferred prosthesis, the systematic review and meta-analysis by Wilasrusmee et al revealed that there is a 54% higher graft patency in biological grafts compared to ePTFE in femoropopliteal bypass procedures and vascular access grafts 21 .…”

Section: Discussionmentioning

confidence: 99%

Long term results of arterial revascularization with Omniflow II biosynthetic grafts: a single center experience

ŞİMŞEK,

AZBOY,

TEMİZTÜRK

2023

J Cukurova Anesth Surg

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Objective: The aim of this study is to analyze the long-term outcomes of above-knee femoro-popliteal bypass procedures with Omniflow II biosynthetic grafts. Primary patency and graft related complications were the end points of the study. Methods: Between January 2012 and January 2021, a total of 50 patients (42 males, 8 females) were revascularized using an in-situ Omniflow II graft. Demographic, clinical, operative and postoperative characteristics of the patients were analyzed retrospectively. Results: Mean age was 63.8±10.1 (range 40-82) years. Fifty above-knee femoropopliteal bypass procedures were performed. Four patients (8%) were operated on due to a previous vascular graft infection where 8 (16%) were operated on due to a previous occlusion. Primary patency rate was 88%. Early graft thrombosis occurred in 2 (4%) patients where late graft stenosis unrelated to the anastomotic sites was encountered in 1 (2%) patient. An endarterectomy on either the proximal or distal site of the anastomosis were performed in 12 (24%) patients. Mean follow-up was 32.9±20.8 (range 12-90) months. Three (6%) patients died due to a COVID-19 infection. No graft infection nor mortality related to arterial bypass procedures was encountered. Conclusion: The Omniflow II biosynthetic graft provides superior results in treatment of above-knee femoro-popliteal bypass procedures with high patency rates and low incidence of graft infection and aneurysm formation

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Section: Discussionmentioning

confidence: 99%

Long term results of arterial revascularization with Omniflow II biosynthetic grafts: a single center experience

ŞİMŞEK,

AZBOY,

TEMİZTÜRK

2023

J Cukurova Anesth Surg

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“…Moreover, there are no data on large randomized studies. The authors of one metaanalysis published in 2017 have shown that generally, bioprostheses outperform the analogs made of PTFE in long-term patency, however, there is no information available for evidence-based opinion [6].…”

Section: Relevancy Of the Problemmentioning

confidence: 99%

Biological Analogs of Infrainguinal Arteries: Evolution and Development Prospects (Review)

Zhuravleva¹,

Zhuravleva²,

Zhulkov³

et al. 2017

Sovrem Tehnol Med

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Currently, the gold standard of plastic material for infrainguinal artery replacement is still autovein, however, not infrequently the necessity for prostheses arises.The review presents the characteristics of xeno-and allogenic prostheses for lower limb arteries, which have been used in vascular surgery worldwide since 1960-ies till the present.There have been analyzed the clinical results with the bioprostheses, their advantages and disadvantages being discussed. We have shown that the approach based on chemically cross-linked human and animal tissues used for bioprostheses is limited in its further development.We have studied the evolution of tissue engineering vascular grafts (TEVG), and carried out a critical review of current state of the issue, and presented further paths of its development.

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“…The resultant scaffold is ready for cell colonization as a base for tissue engineering constructs or for use as an autonomous entity with potentially high biocompatibility ( 3 ). It is suggested that such vascular scaffolds outperform synthetic vessels in terms of hemocompatibility and provide a more physiological mechanical match between the prosthetic graft and the host artery ( 4 , 5 ). Additionally, they may provide a valuable alternative to small-diameter vessel (<6 mm) autografts, where polymeric vessels are not applicable due to their high thrombogenicity and compliance mismatch ( 3 , 6 , 7 ).…”

Section: Introductionmentioning

confidence: 99%

Enhancing decellularized vascular scaffolds with PVDF and PCL reinforcement: a fused deposition modeling approach

Klyshnikov,

Rezvova,

Belikov

et al. 2023

Front. Cardiovasc. Med.

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BackgroundDecellularized xenogenic scaffolds represent a promising substrate for tissue-engineered vascular prostheses, particularly those with smaller diameters (<6 mm). Despite their benefits, a notable limitation presents itself during decellularization, namely, the diminished mechanical strength that introduces the risk of aneurysmal dilations in the early post-implantation period. This study introduces a strategy for modification the mechanical properties of these biological scaffolds through the forming of an external polymeric reinforcement via thermal extrusion.MethodsThe study utilized scaffolds fabricated from bovine internal mammary arteries through decellularization and preservation. The scaffolds were divided into subgroups and reinforced with polymeric helices made of Polyvinylidene fluoride (PVDF) and Polycaprolactone (PCL), n = 5 for each. An experimental setup for external reinforcement coating was designed. Computed microtomography was employed to obtain accurate 3D models of the scaffolds. Mechanical properties were evaluated through in vitro uniaxial tension tests (Z50, Zwick/Roell, Germany), compliance evaluation and numerical simulations (Abaqus/CAE, Dassault Systemes, France) to investigate the effect of external reinforcement on aneurysm growth.ResultsUsing a double-layer helix for the reinforcement significantly enhanced the radial tensile strength of the scaffolds, increasing it up to 2.26 times. Yet, the comparison of vessel's compliance between two reinforced and the Control scaffolds within the physiological pressures range did not reveal any significant differences. Numerical simulation of aneurysm growth showed that thin-walled regions of the Control scaffold developed aneurysmal-type protrusions, bulging up to 0.7 mm, with a substantial degradation of mechanical properties. In contrast, both PVDF and PCL reinforced scaffolds did not exhibit significant property degradation, with deformations ranging 0.1–0.13 mm depending on the model, and a maximum decrease in the modulus of elasticity of 23%.ConclusionThe results of the study demonstrated that the external polymer helical reinforcement of decellularized scaffolds via thermal extrusion enables a controlled modification of mechanical properties, notably enhancing radial strength while maintaining sufficient compliance within the physiological pressure range. A series of in vitro tests demonstrated the consistency and potential of this approach for decellularized xenogenic scaffolds, a concept that had not been explored before.

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Clinical results of biologic prosthesis: A systematic review and meta-analysis of comparative studies

Cited by 9 publications

References 17 publications

Long term results of arterial revascularization with Omniflow II biosynthetic grafts: a single center experience

Long term results of arterial revascularization with Omniflow II biosynthetic grafts: a single center experience

Biological Analogs of Infrainguinal Arteries: Evolution and Development Prospects (Review)

Enhancing decellularized vascular scaffolds with PVDF and PCL reinforcement: a fused deposition modeling approach

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