Clinical, radiographic, biochemical and histological findings of florid cemento-osseous dysplasia and report of a case

Abstract

Florid cemento-osseous dysplasia has been described as a condition that characteristically affects the jaws of middle-aged black women. It usually manifests as multiple radiopaque cementum-like masses distributed throughout the jaws. This condition has also been classified as gigantiform cementoma, chronic sclerosing osteomyelitis, sclerosing osteitis, multiple estenosis and sclerotic cemental masses. The authors present a case of an uncomplicated florid cemento-osseous dysplasia in a 48-year-old black woman. Multiple sclerotic masses with radiolucent border in the mandible were identified radiographically. Histopathologic findings revealed formation of calcified dense sclerotic masses similar to cementum. All clinical, radiographic, biochemical and histological features were suggestive of the diagnosis of florid cemento-osseous dysplasia.

Florid cemento-osseous dysplasia and osteomyelitis: a case report of a simultaneous presentation

“…Management of these conditions involves clinical-radiographic follow-up. Endodontic therapy should not be done before a definitive diagnosis is obtained, especially when it is based solely on radiographic findings without other signs and symptoms (7).…”

“…Another disease that may resemble the FCOD is chronic diffuse sclerosing osteomyelitis (CDSO) (7). It appears as a single, poorly delineated opaque segment of the mandible (13), whereas FCOD is seen as multiple round or lobulated opaque masses.…”

“…FCOD is a benign, non-neoplastic lesion and very rare condition in the jaws, most commonly seen in middle-aged black women, although it also may occur in Caucasians and Asians (6,7). The authors use several terminologies, such as multiple enostoses, multiple cemento-ossifying fibromas, multiple periapical osteofibromatosis, florid cementoosseous dysplasia and gigantiform cementoma.…”

“…Radiographically, FCOD appears as dense, lobulated masses, often symmetrically located in various regions of the jaws (7). Symptoms such as dull pain or drainage are almost always associated with exposure of sclerotic calcified masses in the oral cavity, i.e., secondary osteomyelitis (8).…”

Manifestações imaginológicas distintas na displasia cemento-óssea florida

“…A etiologia dessa patologia é desconhecida e apresenta-se totalmente assintomáti-ca 1-2,6-7 e, em muitos casos, as lesões são detectadas em uma radiografia tomada para outros fins [3][4][5][7][8][9][10] . Tal doença possui maior expressão no gênero feminino, em pacientes melanodermas de meia idade [2][3][4][5][6][7][8]10 . Microscopicamente, essas lesões são compostas de trabéculas ósseas anastomosadas e camadas de calcificações cementoides embutidas em um tecido fibroblástico 7,9 .…”