Clinical Profile of Febrile Thrombocytopenia: A Hospital-Based Cross-Sectional Study

Haemorrhagic Tendencies in Patients Presenting with Fever and Thrombocytopenia in a hospital setting - A Cross Sectional Study

“…Among these 123 cases, 48(39.6%) had platelet count between 50,000 and 20,000, followed by 44 (35.7%) who had count between 100,000 to 50,000, and 31 (25.2%) had severe thrombocytopenia (Platelet count <20,000). These findings correlate with Nair et al study (5) , Modi et al study (8) and Bhalara et al study (2) .…”

A Study of Febrile Thrombocytopenia

“…The incidence of septicemia was 0.8% in the study by Fawas M N et al 7 , 8% each in the studies by suneetha et al 8 , Naveen Kulkarni et al 10 , 12.5% in the study by Hariprasad S et al 9 The incidence of enteric fever was 6.5% in the study by Naveen Kulkarni et al 10 , 2% in the study by suneetha et al 8 , 1.8% in the study by Yadav and Singhai et al 11 , 0% in the studies by Fawas M N et al 7 and Hariprasad S et al 9 The incidence of malaria is 28.5% in the study by Hariprasad S et al 9 , 24.4% in the study by Yadav and Singhai et al 11 , 13% in the study by Naveen Kulkarni et al 10 and lower incidence of 2% in the study by Suneetha et al 8 The incidence of hematological malignancy was reported of 0.6% in the study by Yadav and Singhai et al 11 , 1.79% in the study by Gandhi A A et al 5 which was 0.23% in our study. HIV was reported as viral fever in the study by Modi T et al 6 , 5% patients of study by Gondhali MP et al 12 and which was reported as 1(0.11%) patient in our study. In our study 59.53% patients had platelet count within 50000-100000/ mm 3 range compared to 57.14% in study by Gandhi A A et al 5 , 53% in Fawas M N et al 7 , 53.8% in Yadav and Singhai et al 11 In our study 4% of patients had platelet count less than 20000, compared to study by Gandhi A A et al 5 which is 13.39%, in Fawas M N et al 7 5% and in Yadav and Singhai et al 11 11.8%.…”

“…Majority of patients (92.5%) were in the age group of 18-40 years constituting 92.5% with mean±SD was 39.8±20.1 In our study seasonal variation was seen in 564 (65%) patients during July to September especially in cases of rickettsial fever. In study by Modi T et al 6 , 71.24% patients of febrile thrombocytopenia were seen during rainy and early winter season. In our study fever(100%) was the commonest symptom followed by myalgia(86.5%), headache (84.7%), vomiting (38.6%), pain abdomen (29%), arthralgia (15.7%), diarrhoea (8.7%), altered sensorium (0.58%), seizures (0.35%).In study by Gondhali M P et al 12 90% had headache, 92% had bodyache, 43% nausea, 24% abdominal pain, 15% altered sensorium.…”

Study of Aetiology and Clinical Features of Febrile Thrombocytopenia

“…Platelet Count (/mm 3 In this study, bleeding manifestations are present in 4 out of 9 (44.4%) cases of severe, 8 out of 17 (47%) cases of moderate and 2 out of 24 (8.3%) of mild thrombocytopenia cases. Melena was the most common presenting manifestation followed by petechiae and haematochezia.…”

“…5 Another prospective study, which was conducted on 228 patients with fever and thrombocytopenia in medical unit of Hayatabad Medical Complex during 2008 -2010 was showing malaria as the commonest cause (53%), in which 68% were having falciparum malaria. 6 While Modi T et al study 3 and Raikar et al study 7 had viral aetiology as the major cause of febrile thrombocytopenia. Present study reveals that severe thrombocytopenia (Platelet < 20000/mm 3 ) is present in 18% of cases, moderate thrombocytopenia (20000 -50000/mm 3 ) in 34% and mild thrombocytopenia (> 50000/mm 3 ) is present in 48% of cases.…”