Clinical Profile of Cases of COVID-19 in Far Western Province of Nepal

Joshi, Jagadish; Mishra, Pradip; Kamar, Sher Bahadur; Sharma, Nirajan Datta; Parajuli, Janaki; Sharma, Seema; Pandey, Hem Raj

doi:10.33314/jnhrc.v18i1.2602

Cited by 12 publications

(13 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The earliest data to emerge from across the world have consistently described patients who have presented with a milder illness and have rapidly recovered [9,[15][16]. Kim et al observed 213 COVID-19 patients in South Korea and found that 19% remained asymptomatic [14].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Profile of Patients Suspected to be COVID-19: A Retrospective Analysis of Early Pandemic Data

Goel¹,

Raizada²,

Bansal³

et al. 2020

Cureus

View full text Add to dashboard Cite

Background and Objectives Coronavirus disease 2019 (COVID-19), a global public health emergency of profound magnitude, has brought life to an unprecedented near-standstill. The clinical profile of the disease is still emerging and is marked by considerable geographical variability in terms of transmissibility, clinical profile, virulence, and mortality of the disease. As clinical data is being reported from around the globe, it becomes important to focus on local subjects in a global milieu, lest one misses the trees for the forest. Our study is a short retrospective analysis of the demographic and clinical profiles of subjects presenting with a mild flu-like illness to our hospital who were tested for COVID-19. It compares the differences in age and sex of those who tested positive with those negative. In addition, it reviews the length of time it might take for a case testing positive on reverse transcriptase-polymerase chain reaction (RT-PCR) test to become negative. Methodology A retrospective analysis of data from adults who presented to our hospital with a mild flu-like illness between the months of March and May 2020 was conducted to understand the disease profile. The nasal/oropharyngeal swabs were collected from each patient and were transported to state-approved laboratories chain for RT-PCR analysis. Information was collected from reports received, clinical information forms, and sample collection forms that were being maintained as a part of the clinical management protocol. Data were analysed using Stata software, version 13 (StataCorp LLC, College Station, TX, USA). Observations and Results Three thousand twenty-six subjects presented to our hospital with either mild flu-like symptoms or with suspected exposure to a confirmed case of COVID-19. The subjects had a mean age of 37.3 (± 15.1) years and 1,805 (60.3%) were males. A regression analysis revealed an adjusted odds of 1.6 (95% confidence interval (CI): 1.2, 2.1) for testing positive for males as compared to females. For every one year increase in age, the odds for testing positive increased by 1.02 (95% CI: 1.01, 1.03). Of the 2,592 individuals for whom data was available, 201 (7.6%) were found positive on RT-PCR 1, 2 2 2 2 3 4

show abstract

Section: Discussionmentioning

confidence: 99%

“…Others had a cough (40%) and hypoxia (40%). Joshi et al described nine relatively younger men in a small case series from Nepal who had a mean age of 20 -40 years [15].…”

Section: Discussionmentioning

confidence: 99%

Profile of Patients Suspected to be COVID-19: A Retrospective Analysis of Early Pandemic Data

Goel¹,

Raizada²,

Bansal³

et al. 2020

Cureus

View full text Add to dashboard Cite

show abstract

“…This prevalence also might not represent national level prevalence as samples from random populations have not been tested. Early studies reported that COVID-19 patients in Nepal showed few or no symptoms at all (24,36). The situation updates of the Ministry of Health and Population (MoHP) also indicates that most of the confirmed cases are found through active surveillance and contact tracing rather than patients visiting hospitals with symptoms (25).…”

Section: Discussionmentioning

confidence: 99%

Early Epidemiological Features of COVID-19 in Nepal and Public Health Response

Dhakal

Karki²

2020

Front. Med.

View full text Add to dashboard Cite

Coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), was first reported in late 2019 from Wuhan, China. Considering COVID-19's alarming levels of spread and severity, the World Health Organization (WHO) declared a global pandemic on March 11, 2020. The first case of COVID-19 in Nepal was reported on January 23, 2020. The Government of Nepal implemented different public health measures to contain COVID-19, including border closures and a countrywide lockdown. We collected the daily data provided by the Ministry of Health and Population (MoHP) of the Government of Nepal and illustrated the early epidemiological characteristics of COVID-19 in Nepal. By May 31, 2020, 1,572 cases and eight deaths were reported in Nepal associated with COVID-19. The estimate of prevalence for COVID-19 among tested populations was 2.25% (95% CI: 2.15-2.37%) and case-fatality rate was 0.5%. The majority of the cases were young males (n = 1,454, 92%), with overall average age being 30.5 years (ranging from 2 months to 81 years) and were mostly asymptomatic. There were only five cases from three districts until the end of March, but cases surged from April and spread to 57 out of 77 districts of Nepal by the end of May 2020 despite the continuous lockdown. Most of these cases are from the southern plains of Nepal, bordering India. As the effect of COVID-19 is expected to persist longer, the Government of Nepal should make appropriate strategies for loosening lockdowns in a phase-wise manner while maintaining social distancing and personal hygiene and increasing its testing, tracking, and medical capacity.

show abstract

“…1.1% of the cases were symptomatic and were in isolation, death was reported to be among 1.1% of the COVID 19 patients [13]. According to research performed by Joshi J et al on the clinical profile of COVID 19 patients in the far Western province (Sudurpashchim Pradesh) of Nepal showed that the patients who were COVID-19 positive were generally males and that they were between 20-40 years in age [23]. This is highly varied from findings in China as according to a study conducted in China proved the average age of the COVID-19 cases to be 55•5 years [24].…”

Section: Age Of the Covid-19 Positive Patients In Nepal Vs Global Datamentioning

confidence: 99%

“…According to research performed by Joshi J et al on the clinical profile of COVID 19 patients in the far Western province (Sudurpashchim Pradesh) of Nepal it became evident that the majority of these COVID-19 positive cases were male; superimposed to this was the fact that these males were between 20-40 years in age [23]. According to a report published by the Ministry of Health and population, May 22, 2020, It was stated that bulk of the cases were of the ages between 21 to 30 years.…”

Section: Age Of Covid 19 Positive Patients In Nepalmentioning

confidence: 99%

The changing pattern of COVID-19 in Nepal: A Global concern- A Narrative Review

Banerjee¹,

Robinson²,

Kashyap³

et al. 2020

Nepal J Epidemiology

View full text Add to dashboard Cite

This narrative review of the literature aims to assess the impact of COVID-19 on the younger age group in terms of the Global mortality of COVID-19 in comparison to Nepal. An extensive literature survey of English literature was conducted using Pubmed, Medline, Google Scholar, Embase, WHO Nepal Situation Updates on COVID-19, Situation update report, Ministry of Health and Population-Nepal from January 25, 2020 to June20, 2020. According to the Ministry of Health and population of The Government of Nepal, as of June 20 , 2020, out of a total of 8,605 laboratory confirmed cases reported to date, the pattern shows that most of the cases fell into the cohort of 21-30 years (37.72%), followed by 11-20 years (24.35 %), 31-40 years (21.97%) and 41-50 years (9.2%). To date Nepal has recorded a total of twenty-two deaths. At first evaluation thesefigures may not strike one as alarming, but on further investigation it is noted that the mean age is 42. 32 ± 19.632 SD years, and out of which male patients accounted for 77.3% and female accounted for 22.7%. The current situation of COVID-19 and how it develops in Nepal should be closely monitored and could be of international concern as it may be the early indicator of a changing pattern in COVID-19 infections. Nepal maytherefore act as a global watch dog, due to the fact that the world could very possibly expose the younger age group under the notion that they are more resilient to the virus, when in reality that notion may be changing. This trend must be monitored and further investigated in order to establish the risk of the events unfolding in Nepal.

show abstract

Clinical Profile of Cases of COVID-19 in Far Western Province of Nepal

Cited by 12 publications

References 0 publications

Profile of Patients Suspected to be COVID-19: A Retrospective Analysis of Early Pandemic Data

Profile of Patients Suspected to be COVID-19: A Retrospective Analysis of Early Pandemic Data

Early Epidemiological Features of COVID-19 in Nepal and Public Health Response

The changing pattern of COVID-19 in Nepal: A Global concern- A Narrative Review

Contact Info

Product

Resources

About