Clinical outcomes of atypical extra-esophageal reflux symptoms following laparoscopic antireflux surgery

Brown, Shaun R.; Gyawali, C. Prakash; Melman, Lora; Jenkins, Eric D.; Bader, Julia; Frisella, Margaret M.; Brunt, L. Michael; Eagon, J. Christopher; Matthews, Brent D.

doi:10.1007/s00464-011-1806-y

Cited by 32 publications

(22 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Moreover, there was no difference in the rates of complete symptom control according to the presence of atypical symptoms. The results of this study also support the findings of Brown et al [14], who described a good response to laparoscopic Nissen fundoplication in GERD patients with atypical symptoms after judicious evaluation and proper patient choice.…”

Section: Discussionsupporting

confidence: 91%

Factors predicting outcomes of laparoscopic Nissen fundoplication for gastroesophageal reflux disease: experience at a single institution in Korea

Park

Kim

et al. 2017

Ann Surg Treat Res

View full text Add to dashboard Cite

PurposeLaparoscopic fundoplication is considered the standard surgical treatment for gastroesophageal reflux disease (GERD) in Western countries. However, some patients experience poor surgical outcomes with this procedure. The study aimed to identify the predictive factors of the surgical outcomes of laparoscopic Nissen fundoplication for the treatment of Korean GERD patients.MethodsSixty-one patients with GERD were treated using laparoscopic Nissen fundoplication between November 2012 and February 2015. Symptom control rates were compared according to clinical and surgical factors to identify predictive factors of successful surgical outcomes.ResultsThirty-five men and 26 women were enrolled. Preoperatively, typical symptoms were present in 60 patients (98%), while atypical symptoms were present in 40 patients (66%). Postoperatively, typical symptoms were controlled in 51 of 60 patients (85.0%), while atypical symptoms were controlled in 33 of 40 patients (82.5%). Overall, at 6 months postsurgery, 54 (88.5%) reported some resolution of GERD symptoms, with 48 (78.7%) achieving complete control. Patients who exhibited a good response to proton pump inhibitor therapy had a significantly greater rate of complete symptom control (P = 0.035).ConclusionLaparoscopic fundoplication is effective for controlling GERD symptoms. Response to preoperative proton pump inhibitor was a predictor of successful outcome.

show abstract

Section: Discussionsupporting

confidence: 91%

Factors predicting outcomes of laparoscopic Nissen fundoplication for gastroesophageal reflux disease: experience at a single institution in Korea

Park

Kim

et al. 2017

Ann Surg Treat Res

View full text Add to dashboard Cite

show abstract

“…8,[23][24][25] Chest pain symptom resolution in these studies ranged from 48% to 96% with fundoplication, regardless of the type of surgery. 7,[22][23][24] In one study, 87% of patients with NCCP treated with surgical fundoplication stated that they would consider the operation again if needed 22 (Table 2). Some studies have shown no difference in chest pain symptom scores after surgical fundoplication in patients with documented oesophageal dysmotility as the underlying cause of NCCP.…”

Section: Proton Pump Inhibitors (Ppis)mentioning

confidence: 77%

“…In one study, a significant improvement in atypical symptoms (including chest pain) was seen in patients with normal and spastic oesophageal motility patterns treated with surgical fundoplication (72.4% vs. 83.9%, respectively) compared to pre‐operative symptom scores ( P = 0.04). Those patients with hypocontractile oesophageal motor disorders had improved symptoms (21.7%), but at a lower rate of improvement compared to those with spastic or normal oesophageal motility patterns (Table ) …”

Section: Resultsmentioning

confidence: 99%

Review article: the current treatment of non‐cardiac chest pain

George

Abdallah

Maradey–Romero

et al. 2015

Aliment Pharmacol Ther

View full text Add to dashboard Cite

show abstract

“…The concept of tailoring the fundoplication (partial vs. complete) based upon manometric findings of ineffective esophageal motility is debated [37]. However, information on esophageal contractility is helpful to prognosticate the outcome, if not to influence the selection of a partial fundoplication [4,38,39].…”

Section: Antireflux Surgerymentioning

confidence: 99%

What Is the Impact of High-Resolution Manometry in the Functional Diagnostic Workup of Gastroesophageal Reflux Disease

Keller¹

2018

Visc Med

View full text Add to dashboard Cite

International guidelines agree that high-resolution esophageal manometry (HRM) is an integral part of the diagnostic evaluation of patients with refractory reflux symptoms and should be performed before antireflux surgery. Its most important goal is to explore differential diagnoses, in particular major esophageal motility disturbances, that may be responsible for symptoms. HRM additionally provides insights into all relevant pathomechanisms of gastroesophageal reflux disease (GERD): It can reveal important information on the morphology and function of the esophagogastric junction (EGJ), the presence of a hiatus hernia, transient lower esophageal sphincter relaxations, and dysmotility of the esophageal body. To obtain this information, a 3-step hierarchical system has been proposed for the algorithmic characterization of esophageal motor function. The first step is to investigate the morphology and contractility of the EGJ, the second to monitor esophageal body motor patterns in response to water swallows, and the third to determine the contraction reserve in patients with abnormal esophageal motor function using provocation tests. Observations made with HRM can not only explain the cause of symptoms in GERD patients but may also have the potential to direct specific treatment.

show abstract

Clinical outcomes of atypical extra-esophageal reflux symptoms following laparoscopic antireflux surgery

Cited by 32 publications

References 23 publications

Factors predicting outcomes of laparoscopic Nissen fundoplication for gastroesophageal reflux disease: experience at a single institution in Korea

Factors predicting outcomes of laparoscopic Nissen fundoplication for gastroesophageal reflux disease: experience at a single institution in Korea

Review article: the current treatment of non‐cardiac chest pain

What Is the Impact of High-Resolution Manometry in the Functional Diagnostic Workup of Gastroesophageal Reflux Disease

Contact Info

Product

Resources

About