Clinical Observations of Effects on Central Nervous System in Patients With Acute Facial Palsy

Tumor necrosis factor‐α response and herpesvirus infection in bell's palsy

“…As an indication of the possible transient nature of the infection, we found a spontaneous recovery of nerve function in 90% of our patients with Bell's palsy. This was in agreement with our previous observations, 23 as well as with reports of others 16 . In an experimental model of Bell's palsy, nerve dysfunction developed between 6 and 9 days after HSV‐1 virus inoculation and continued for 3 to 7 days and then resolved spontaneously 24 .…”

Bilateral Facial Nerve Palsy following Head Injury: A Report of Two Uncommon Cases

“…Literature review reveals that surgery is not advisable beyond 2 weeks, because regeneration stage has already begun. [11][12][13] Most cases are associated with concussion and edema of the nerve and may improve conservatively with steroids and physiotherapy. 13 According to a study (Fisch et al) an early surgical intervention is warranted if ENoG indicates 90% amplitude reduction within 6 days post injury.…”

Simultaneous Bilateral Facial Nerve Palsy- Case Series and Review of Literature

“…The role of acyclovir in its treatment is still controversial [11]. Patients not responding to conservative management should be assessed for facial nerve decompression [12]. Although the role of surgery (facial nerve decompression) has remained controversial amongst some of the otologists; therefore we suggest that ENoG and the clinical course of paralysis are the best guidelines for selecting patients for facial nerve decompression.…”

“…Surgery is not advisable after 14 days, because the active viral disease has abated already and the early regeneration stage is beginning. Decompression must involve both the meatal and labyrinthine segments and is usually done via a middle cranial fossa approach [12].…”