2020
DOI: 10.1016/j.ijid.2019.10.030
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: To evaluate the clinical, laboratory, and immune characteristics of Zika virus (ZIKV)-associated encephalitis in pediatric patients after the epidemic in Huila, southern Colombia. Methods: A pediatric neuro-surveillance hospital study was conducted in a referral health center in southern Colombia, from October 2016 to October 2017. Cases of encephalitis were confirmed by nucleic acid amplification tests and serological methods in cerebrospinal fluid (CSF), plasma, and/or urine. Levels of six cytokines were eva… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

0
28
0

Year Published

2020
2020
2023
2023

Publication Types

Select...
4
4

Relationship

0
8

Authors

Journals

citations
Cited by 20 publications
(28 citation statements)
references
References 36 publications
0
28
0
Order By: Relevance
“…According to the OCEBM Levels of Evidence, the one cohort study was graded Level 1b. Within the case series, the study quality varied, reflecting differences in population sampling and study design, with one case series rated good [ 47 ], five of the case series rated fair [ 41 , 42 , 44 , 45 , 49 ], and three studies rated poor [ 40 , 43 , 46 ] ( S2 Table ).…”
Section: Resultsmentioning
confidence: 99%
See 2 more Smart Citations
“…According to the OCEBM Levels of Evidence, the one cohort study was graded Level 1b. Within the case series, the study quality varied, reflecting differences in population sampling and study design, with one case series rated good [ 47 ], five of the case series rated fair [ 41 , 42 , 44 , 45 , 49 ], and three studies rated poor [ 40 , 43 , 46 ] ( S2 Table ).…”
Section: Resultsmentioning
confidence: 99%
“…In all but one study, confirmatory testing for ZIKV was performed if cases presented with at least one common sign or symptom of ZIKV infection. In the remaining study, confirmatory testing was performed if cases presented with signs of encephalitis [ 47 ]. Confirmation of ZIKV infections was performed exclusively using laboratory assays in all except one study [ 40 ], which made use of a variety of patient records to ascertain ZIKV diagnosis based on CSTE criteria.…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…In recent years, new viruses such as chikungunya (CHIKV) and Zika (ZIKV) have also been introduced. In recent years after the ZIKV epidemic, cases of ZIKV infection have continued to be observed, and in children, according to Salgado et al [30], there were found patients with encephalitis with coinfection of DENV and ZIKV.…”
Section: Signs and Symptoms In Coinfectionsmentioning
confidence: 99%
“…Extensive research has revealed that ZIKV has a wide tissue tropism and can cross the placental barrier of pregnant women, thus interfering with proper neurological development in the fetus (6)(7)(8). ZIKV has also been found to cause neuroinflammatory disorders in a fraction of otherwise healthy adults and children (9,10). Amongst the most worrying features of ZIKV is perhaps the fact that infectious virus may persist in the testis and the virus may therefore be transmitted sexually (11).…”
Section: Introductionmentioning
confidence: 99%