“…Although the global burden and prevalence of frailty are not well known, some general patterns have emerged: it is more frequent in women than men, increases with aging (even though it is present in all age groups), and is more common in lower socio-economic groups and ethnic minorities [1,2]. Evidence is growing around the impact of frailty in the ICU [3–6] and after severe brain damage [7 ▪ ,8,9 ▪ ,10,11,12 ▪ ]. Frailty is associated with higher mortality in older patients and is related to a broad spectrum of ‘geriatric conditions’ such as dementia, cognitive decline, disability, falls, fractures, loneliness, worsening mobility, lower quality of life, hospitalization, and dependence on home nursing [13].…”