Clinical immunological characteristic of patients with tick-borne encephalitis during the sharp period in Tomsk Region

Abstract

Results of complex research of features of clinical and immunological profiles tick-borne encephalitis during the sharp period in Tomsk Region are resulted in the article. Last years redistribution of a parity of clinical displays of the sharp period in favor of prevalence of feverish forms of disease and a tendency to increase in cases of long circulation of an antigene of a virus tick-borne encephalitis is marked. One of the important reasons of such effect is decrease in immunological reactance of an organism with development of cytokine’s disbalance and expression infringement receptors of cytokines with lymphocytic cages.

Clinical Case of Mixed Infection: Tick-borne Encephalitis and Borreliosis in the Republic of Sakha (Yakutia)

“…Currently, published researches indicate the presence of features of the interaction of the causative agents of tick-borne encephalitis and tick-borne borreliosis in mixed infection [10,13,14,26]. At the same time, special attention is paid to the focal form of mixed tick-borne encephalitis-borreliosis infection, characterized by damage to the nervous system with the development of persistent neurological disorders and possible death [2, 16,22,27].…”