Clinical features of Behçet's disease in children

Abstract

The findings of BD in children are similar as in adults, but the frequency of familial cases is significantly higher.

Juvenile Adamantiades-Behçet Disease

“…Genital ulcers are more frequent in girls than in boys (50-61% vs. 75-96%) [15,24]. In boys, they are mostly localized in the scrotum and pubis and rarely in the penis, whereas in girls they appear at the major labiae and rarely in the vagina [13]. Perianal and extragenital ulcers can also be observed [30,33].…”

“…The familial prevalence among patients with JABD ranges widely from 12 to 15 [7,15,30] to 22.5-25 [6,21] and 42-55% [13,14,16]. …”

“…They usually leave a scar on the involved skin or mucosa [13]. Nevertheless, scarring is less frequent in JABD than in AABD patients [34].…”

“…Recurrent genital ulcers are the second most frequent manifestation in JABD, and their frequency ranges from 58 to 94% [7,13,15,21,31,33]. They usually leave a scar on the involved skin or mucosa [13].…”

“…Since the publication of the first article on the pediatric disease by Mundy and Miller in 1978 [8], several case reports and case studies have been described [6,7,9,10,11,12,13,14]. However, reviews on this subject are rather scarce [6,15,16,17,18].…”