Clinical Features, Familial History, and Migraine Precursors in Patients With Definite Vestibular Migraine: The VM‐Phenotypes Projects

Teggi, Roberto; Colombo, Bruno; Albera, Roberto; Libonati, Giacinto Asprella; Balzanelli, Cristiano; Batuecas‐Caletrío, Ángel; Casani, Augusto Pietro; Espinoza-Sanchez, Juan Manuel; Gamba, Paolo; Lopez-Escamez, José A.; Lucisano, Sergio; Mandalà, Marco; Neri, G; Nuti, Daniele; Pecci, Raffaella; Russo, Antonio; Martín-Sanz, Eduardo; Sanz, Ricardo; Tedeschi, Gioacchino; Torelli, Paola; Vannucchi, Paola; Comı, Gıancarlo; Bussi, Mario

doi:10.1111/head.13240

Cited by 78 publications

(94 citation statements)

References 33 publications

(54 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The average age of onset of VM was 44.3 (±13.7) years, on the upper end of the previously reported range (typically late 30s to mid‐40s) . The female preponderance of 4:1 we found is consistent with the 1.5–5.6:1 female predominance reported in other studies . Most had a personal and family history of migraine headaches, consistent with the findings in other studies .…”

Section: Discussionsupporting

confidence: 91%

“…Just over 10% of our patients described ictal osmophobia, slightly lower than 15% reported in a smaller study . The large proportion with ictal aural symptoms agrees with the frequency (up to 69%), usually tinnitus, reported by others . Reversible cognitive dysfunction, reported by some of our patients, is a known feature of migraine attacks .…”

Section: Discussionsupporting

confidence: 86%

“…Visual aura occurred in 27.5% of our patients which falls within the range (one‐quarter to one‐third) observed elsewhere . Photophobia and phonophobia were more frequently reported by our patients compared to other studies (up to 70%) . Just over 10% of our patients described ictal osmophobia, slightly lower than 15% reported in a smaller study .…”

Section: Discussionsupporting

confidence: 74%

“…Ictal VIV was documented in 2 other studies in about 20% of their patients, about half the proportion of our cohort. Only 1 study reported directional pulsion (19.8% with lateropulsion, 15% with antero‐retro pulsion …”

Section: Discussionmentioning

confidence: 43%

See 3 more Smart Citations

The Spectrum of Vestibular Migraine: Clinical Features, Triggers, and Examination Findings

et al. 2019

View full text Add to dashboard Cite

Objective To assess the ictal symptoms, interictal symptoms, psychiatric comorbidities, and interictal neuro‐otologic examination findings in vestibular migraine (VM). Methods Retrospective chart review of 491 patients seen from August 2014 until March 2018 at a tertiary neurology referral center for vestibular disorders to identify patients fulfilling the 2012 VM criteria. Results One hundred and thirty‐one patients (105 women) were identified. Mean age of VM onset was 44.3 (±13.7) years. Preceding the onset of vestibular symptoms, most had migraine (57.3%) and motion sickness (61.1%). It was common to have a family history of migraine (50.8%) and episodic vestibular symptoms (28.1%). Common ictal symptoms were triggered (visually induced and head‐motion) and spontaneous vertigo, accompanied by photophobia and phonophobia (118/131 [90.1%] patients), nausea (105/131 [80.2%] patients), aural symptoms (79/131 [60.3%] patients), and headache (65/131 [49.6%] patients). Interictally, many experienced visually induced (116/131 [88.6%] patients), head‐motion (86/131 [65.6%] patients), and persistent (67/131 [51.1%] patients) dizziness. Psychiatric comorbidities include anxiety (92/131 [70.2%] patients), depression (53/131 [40.5%] patients), insomnia (38/131 [29.0%] patients), phobic disorders (15/131 [11.5%] patients), and psychogenic disorders (11/131 [8.4%] patients). Common triggers were stress (52/131 [39.7%] patients), bright lights (35/131 [26.7%] patients), weather changes (34/131 [26.0%] patients), and sleep deprivation (34/131 [26.0%] patients). Interictal neuro‐otologic examination was abnormal in 56/131 (42.7%), usually hyperventilation‐induced, head‐shaking‐induced, vibration‐induced, and positional nystagmus. The most common balance‐test finding was impaired sharpened Romberg’s test (22/130 [16.9%] patients). Conclusions In this single center study, we found that VM typically affects women in their 40s, with a personal and family history of migraine. Typical ictal symptoms were triggered and spontaneous vertigo, associated with photophobia and phonophobia, nausea, aural symptoms, and headache. Interictal vestibular symptoms, comorbid psychiatric disorders, and non‐specific interictal neuro‐otologic findings were common.

show abstract

Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 86%

Section: Discussionsupporting

confidence: 74%

Section: Discussionmentioning

confidence: 43%

See 2 more Smart Citations

The Spectrum of Vestibular Migraine: Clinical Features, Triggers, and Examination Findings

et al. 2019

View full text Add to dashboard Cite

show abstract

“…This proportion was slightly higher than the prevalence of 7–9% shown in previous studies [27-29]. The association between vertigo and migraine was recognized early on [27, 30, 31].…”

Section: Discussionmentioning

confidence: 64%

Diagnosis of Vertigo and Dizziness Syndromes in a Neurological Outpatient Clinic

Pan¹,

Zhang²,

Long³

et al. 2018

Eur Neurol

View full text Add to dashboard Cite

Background: Dizziness and vertigo are frequent complaints of outpatients in the neurological department. Our objective was to explore the epidemiological category and clinical features of patients with dizziness or vertigo in the neurological outpatient department of a tertiary hospital. Methods: We consecutively recruited all patients with dizziness and/or vertigo visiting the neurological outpatient clinic of the First Affiliated Hospital of Chongqing Medical University from January 2016 to June 2017. All patients were interviewed by 4 neurologists and they completed self-administered questionnaires. General physical and standardized neuro-otology bedside examinations were performed in all participants. Instrumental examinations and other related examinations were prescribed as needed. Results: A total of 392 patients, 272 female and 120 male, were enrolled and the ratio of males to females was 1: 2.27. The mean age was 52.39 ± 13.87 years (range 11–90). Elderly patients (≥60 years) accounted for about one-third of the patients. Peripheral vestibular disorders accounted for 54.6% of patients, central vestibular disorders (including vestibular migraine [VM]) accounted for 22.4% of patients, psychogenic vertigo in 64 (16.3%), other reasons in 9 (2.3%) and unknown in 17 (4.3%). Benign paroxysmal positional vertigo (BPPV; 30.8%), psychiatric dizziness (20.5%), and VM (14.4%) were the 3 major vestibular diseases in patients under 60 years of age; however, BPPV (27.9%), central vertigo (21.7%), and Meniere’s disease (11.7%) were more common in patients over 60 years of age. Conclusions: This study provided a classification and clinical features of vestibular disorders in a neurological outpatient department of a tertiary hospital in China. The spectrum of vertigo or dizziness is different between different age groups and clinicians should pay attention to this difference in clinical reasoning.

show abstract

Functional Dizziness

Azzi

Hochman

2023

Functional Illness of the Head and Neck

View full text Add to dashboard Cite

Clinical Features, Familial History, and Migraine Precursors in Patients With Definite Vestibular Migraine: The VM‐Phenotypes Projects

Abstract: Our results may indicate that vestibular symptoms in pediatric patients may act as a predisposing factor to develop vestibular migraine at an earlier age in adulthood.

Cited by 78 publications

References 33 publications

The Spectrum of Vestibular Migraine: Clinical Features, Triggers, and Examination Findings

The Spectrum of Vestibular Migraine: Clinical Features, Triggers, and Examination Findings

Diagnosis of Vertigo and Dizziness Syndromes in a Neurological Outpatient Clinic

Functional Dizziness

Contact Info

Product

Resources

About