“…The symptoms of the distinctive phenotype of congenital Zika syndrome are severe microcephaly with a collapsed skull and prominent scalp rugae, profound craniofacial disproportion, exuberant external occipital protuberance, brain calcifications in the junction between cortical and subcortical white matter, and malformations of cortical development, often with a simplified gyral pattern and predominance of pachygyria or polymicrogyria in the frontal lobes. Additional findings are enlarged cisterna magna, abnormalities of corpus callosum (hypoplasia or hypogenesis), ventriculomegaly, delayed myelination, and hypoplasia of the cerebellum and the brainstem 3, 4…”