Clinical features and management of 87 patients with pemphigoid gestationis

Abstract

Pemphigoid gestationis is a rare vesiculo-bullous disorder of pregnancy. In this review we summarize the clinical data on 142 pregnancies in 87 patients complicated by pemphigoid gestationis. Our aim is to provide a comprehensive clinical overview of this disease.

Successfully Treated Case of Pemphigoid Gestationis with Post-Partum Intravenous and Oral Steroids

“…Flares also have been observed pre-menses and with the use of oral contraceptives. There is a tendency for PG to recur with subsequent pregnancies, during which there may be an earlier onset and a more severe course; however, skip pregnancies have been reported in 5-8 % of cases [2,3]. Because PG is regarded as a unique entity of immunobullous disease occurring during pregnancy, its management is more difficult because of concerns over the use of systemic therapy during the ante-partum period.…”

Pemphigoid Gestationis (Herpes Gestationis)

“…The etiology of PG is unknown, but there is an increased association with other autoimmune diseases [4][5][6] and HLA antigens: B8, DR3, and DR4 [7,8]. The PG antigen in 180 kD antigen (BPAG2) is present in the hemidesmosomes of the basement membrane [9].…”

Fluconazole induced multifocal bullous eruptions: a case report

“…An initial provisional diagnosis of gestational pemphigoid was made, but later ruled out due to absence of trunk lesion and involvement of face, palm and soles with rapid healing of lesions. 6 On examination multiple pleomorphic bullous lesions were noted in the upper limbs, lower limbs below the knee, face, palm and soles but no mucosal involvement .Some of the blisters…”