Clinical-epidemiologic variation in patients treated in the first and second wave of COVID-19 in Lambayeque, Peru: A cluster analysis

Valladares-Garrido, Mario J.; Failoc‐Rojas, Virgilio E.; Soto-Becerra, Percy; Zeña‐Ñañez, Sandra; Torres-Román, J. Smith; Fernández-Mogollón, Jorge L.; Colchado-Palacios, Irina G.; Apolaya-Segura, Carlos E.; Dávila-Gonzales, Jhoni A.; Arce-Villalobos, Laura R.; Neciosup-Puican, Roxana del Pilar; Calvay-Requejo, Alexander G.; Maguiña, Jorge L.; Apolaya-Segura, Moisés; Díaz-Vélez, Cristian

doi:10.1016/j.ijid.2022.07.045

Cited by 14 publications

(14 citation statements)

References 44 publications

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“…Furthermore, we acknowledge that the incidence of fear of COVID-19 in our study might have been influenced by the timing of our investigations. However, the continuation of significant indicators of lethality and SARS-CoV-2 positivity during the second wave in Peru ( 58 , 59 ), particularly in the Lambayeque region, necessitated the maintenance of strict measures, including social distancing, mandatory social isolation, and targeted quarantines. Frontline personnel, including the military, played a crucial role in ensuring compliance with these measures.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and factors associated with fear of COVID-19 in military personnel during the second epidemic wave in Peru

Valladares-Garrido,

Dominguez-Troncos,

Picón-Reátegui

et al. 2024

Front. Psychiatry

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IntroductionDuring the COVID-19 pandemic, the mounting workload and heightened stress may contribute to exacerbated mental health challenges, including an increased fear of COVID-19, among military personnel. Despite the potential influence of these factors, there remains a scarcity of studies addressing mental health issues, particularly the fear of COVID-19, within this specific population. We aimed to determine the prevalence and factors associated with fear of COVID-19 among military members.MethodsA cross-sectional study was conducted between November 2 and 9, 2021, during the second wave of the COVID-19 pandemic in the Lambayeque region, Peru. The outcome variable was fear of COVID-19, assessed using the Fear of COVID-19 Scale. The association with resilience (Connor-Davidson Resilience Scale, abbreviated as CD-RISC), food insecurity (Household Food Insecurity Access Scale, abbreviated as HFIAS), physical activity (International Physical Activity Questionnaire-Short Form, abbreviated as IPAQ-S), eating disorder (Eating Attitudes Test-26, abbreviated as EAT-26), and other socio- demographic variables was assessed.ResultsAmong the 525 participants, the median age was 22, 95.8% were male, and 19.2% experienced fear of COVID-19. A higher prevalence of fear of COVID-19 was associated with age (PR=1.03; 95% CI: 1.01-1.06), religion (PR=2.05; 95% CI: 1.04-4.05), eating disorder (PR=2.95; 95% CI: 1.99-4.36), and having a relative with mental disorder (PR=2.13; 95% CI: 1.09-4.17). Overweight (PR=0.58; 95% CI: 0.37-0.90) and a high level of resilience (PR=0.63; 95% CI: 0.43-0.93) were associated with a lower prevalence of fear of COVID-19.DiscussionTwo out of ten military personnel were afraid of COVID-19. Our results highlight the need for targeted interventions addressing the factors contributing to fear of COVID-19 among military personnel, emphasizing the significance of mental health support and preventive measures within this specific population.

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Section: Discussionmentioning

confidence: 99%

Prevalence and factors associated with fear of COVID-19 in military personnel during the second epidemic wave in Peru

Valladares-Garrido,

Dominguez-Troncos,

Picón-Reátegui

et al. 2024

Front. Psychiatry

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“…During this period, Peru was affected by three COVID-19 waves: the first was from March 2020 to December 2020 and was associated with the wild-type virus; the second wave was from January 2021 to June 2021, with the Lambda variant; and the third wave took place between January and April 2022, with the Omicron variant ( 22 , 23 ).…”

Section: Methodsmentioning

confidence: 99%

Short-, mid-, and long-term complications after multisystem inflammatory syndrome in children over a 24-month follow-up period in a hospital in Lima-Peru, 2020–2022

Alvarado-Gamarra,

Estupiñan-Vigil,

Garcés-Ghilardi

et al. 2023

Front. Pediatr.

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ObjectiveTo determine the short-, mid-, and long-term complications after multisystem inflammatory syndrome in children (MIS-C) over a 24-month follow-up period in a hospital in Lima, Peru, 2020–2022, and to explore differences according to the immunomodulatory treatment received and type of SARS-CoV-2 virus circulating.MethodsAmbispective 24-month follow-up study in children <14 years of age diagnosed with MIS-C at the Hospital Nacional Edgardo Rebagliati Martins (HNERM).ResultsA total of 62 children were admitted with MIS-C. The most common short-term complications and serious events were intensive care unit (ICU) admission, invasive mechanical ventilation (IMV) due to respiratory failure, and shock; predominantly during the second pandemic wave (lambda predominance) and in children that received intravenous immunoglobulin (IVIG) plus a corticosteroid. Two patients died during the first wave due to MIS-C. During prospective follow-up (median of 24 months; IQR: 16.7–24), only 46.7% of patients were followed for >18–24 months. Of the total, seven (11.3%) patients were identified with some sequelae on discharge. Among the 43 remaining children, sequelae persisted in five (11.6%) cases (neurological, hematological, and skin problems). Six patients (13.9%) presented with new onset disease (hematologic, respiratory, neurological, and psychiatric disorders). One patient died due to acute leukemia during the follow-up period. None of them were admitted to the ICU or presented with MIS-C reactivation. Two patients presented persistence of coronary aneurysm until 8- and 24-month post-discharge.ConclusionIn our hospital, children with MIS-C frequently developed short-term complications and serious events during the acute phase, with less frequent complications in the mid- and long-term. More studies are required to confirm these findings.

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“…However, the study presents strengths. First, to our knowledge, it is the rst study to evaluate this association of variables conducted during the COVID-19 pandemic, particularly during the rst wave, the most critical time in Peru (75)(76)(77)(78)(79). Second, it was possible to capture a broad and varied sample (years of study) of students, and it is reinforced by the strati ed choice of the sample by the university, which will serve as an aid to the strategies of the corresponding institutions.…”

Section: Limitations and Strengthsmentioning

confidence: 99%

Association between Love Breakup and Suicidal Ideation in Peruvian Medical Students: A Cross-Sectional Study during the COVID-19 Pandemic

Valladares-Garrido

Zila-Velasque

Santander-Hernández

et al. 2023

Preprint

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Objective: We aimed to determine the association between a major romantic breakup and suicidal ideation in medical students from three universities in Peru. Methods: A cross-sectional study was conducted during the first pandemic wave in 2021 on medical students from three universities in northern Peru. The outcome was suicidal ideation, measured with question nine of the PHQ-9. The exposure was the experience of a major love breakup during the pandemic. In addition, its association with other covariates (age, sex, family members infected with COVID-19, deceased family members with COVID-19, insomnia, and anxiety, among others) was examined. Results and discussions: Out of 370 students, 19.5% reported a major love breakup during the pandemic (95%CI: 15.5–23.8), and 34.3% had suicidal ideation (95%CI: 29.4–39.4). Having a major love breakup was associated with a higher prevalence of suicidal ideation (PR: 1.49, 95%CI: 1.32–1.67). Moderate insomnia (PR: 2.56, 95%CI: 1.70–3.87) and anxiety symptoms (PR: 1.94, 1.10–3.44) were also associated with suicidal ideation. Conclusion: Our study provides evidence of a significant association between a major love breakup and suicidal ideation. This finding emphasizes the need for further research to better understand this association and inform the development of effective suicide prevention policies in medical education.

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Clinical-epidemiologic variation in patients treated in the first and second wave of COVID-19 in Lambayeque, Peru: A cluster analysis

Cited by 14 publications

References 44 publications

Prevalence and factors associated with fear of COVID-19 in military personnel during the second epidemic wave in Peru

Prevalence and factors associated with fear of COVID-19 in military personnel during the second epidemic wave in Peru

Short-, mid-, and long-term complications after multisystem inflammatory syndrome in children over a 24-month follow-up period in a hospital in Lima-Peru, 2020–2022

Association between Love Breakup and Suicidal Ideation in Peruvian Medical Students: A Cross-Sectional Study during the COVID-19 Pandemic

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