Clinical complications after transvaginal oocyte retrieval in 7,098 IVF cycles

Actinomyces urogenitalis Bacteremia and Tubo-Ovarian Abscess after an In Vitro Fertilization (IVF) Procedure

“…However, the incidence is generally low and varies between 0.03% and 1.3% (7,(21)(22)(23)(24)(25)(26)(27). Transvaginal inoculation of bacteria into the peritoneal cavity or ovary by the collecting needle is the most apparent source of these infections (23,28,29).…”

“…The efficacy of the procedure in preventing infection has been evaluated, resulting in opposite conclusions and recommendations (24,34). The use of prophylactic antibiotics for TVOR is widespread, although the antibiotic used differs greatly: cefoxitin, ceftazidime, cefazolin, and the combination of cefazolin and metronidazole have been proposed (21,22,26,28). The usefulness remains controversial, however, because of the low incidence of post-TVOR pelvic infection whether antibiotics are used or not (23,26,35).…”

Evaluation of complications developing during and after transvaginal ultrasound — guided oocyte retrieval

“…The second complication type, described in a case report by Ayestaran et al (2000), was cardiac conduction disorder, which occurred in a patient who received paracervical anaesthesia with 400 mg mepivacaine [13]. Aside from these cases, no other anaesthesia-induced complications were found in the literature [14,15].…”

Does the number of prior oocyte retrieval practices increase the amount of blood loss in subsequent OPU procedures?

“…Aragona et al reported the incidence of severe complications and intraperitoneal bleeding, in their 7,098 IVF cycle series, to be 0.08% and 0.06%, respectively. 15 However Siristatidis et al reported the rate of severe complications with a higher rate of 0.72%. 1 They indicated minor vaginal bleeding to be the most frequent complication, which emerged in the 18.08% of the patients and was treated easily.…”