Clinical Comparison of Grafts Stored in McCarey-Kaufman Medium at 4°C and in Corneal Organ Culture at 31°C

Pan-Corneal Endothelial Viability Assessment: Application to Endothelial Grafts Predissected by Eye Banks

“…65 Interestingly, although we did not demonstrate it, the same observation can be made for series using 4°C stored corneas: 11% Ϯ 20% at 6 months postoperatively in the Cornea Donor Study. 66,67 Because no difference in either clinical results or ECD has been shown between 4°C and OC stored corneas, 65,68 we think our results could be extrapolated to 4°C storage, where SM performed in eye banks may have the same gap with viable ECD as does TLM in eye banks using OC. This remains to be investigated.…”

Pan-Corneal Endothelial Viability Assessment: Application to Endothelial Grafts Predissected by Eye Banks

“…65 Interestingly, although we did not demonstrate it, the same observation can be made for series using 4°C stored corneas: 11% Ϯ 20% at 6 months postoperatively in the Cornea Donor Study. 66,67 Because no difference in either clinical results or ECD has been shown between 4°C and OC stored corneas, 65,68 we think our results could be extrapolated to 4°C storage, where SM performed in eye banks may have the same gap with viable ECD as does TLM in eye banks using OC. This remains to be investigated.…”

Organ culture, but not hypothermic storage, facilitates the repair of the corneal endothelium following mechanical damage

“…An improvement in the endothelial parameters was also shown in corneas that were first preserved under hypothermic conditions and then transferred for several days to OC (Camposampiero et al 2003). Despite these facts, there is no obvious superiority of one of the storage systems over the other, based on the similar clinical results achieved with grafts prepared by both methods (Rijneveld et al 1992;Frueh & Bo¨hnke 2000).…”

Overview of Short-Term and Intermediate-Term Corneal Storage Solution: Comparison of Clinical Outcomes and Need For Future Research

“…In addition, the activity of antibiotic is limited in refrigerated temperature. In a prospective study, Rijneveld et al 42 did not find any significant difference in visual acuity, central corneal thickness, and ECD for grafts stored in MK storage solution and organ culture. HLA-DR antigen is found to be decreased in the corneas preserved by organ culture.…”

Pan-Corneal Endothelial Viability Assessment: Application to Endothelial Grafts Predissected by Eye Banks

“…65 Interestingly, although we did not demonstrate it, the same observation can be made for series using 4°C stored corneas: 11% Ϯ 20% at 6 months postoperatively in the Cornea Donor Study. 66,67 Because no difference in either clinical results or ECD has been shown between 4°C and OC stored corneas, 65,68 we think our results could be extrapolated to 4°C storage, where SM performed in eye banks may have the same gap with viable ECD as does TLM in eye banks using OC. This remains to be investigated.…”

Organ culture, but not hypothermic storage, facilitates the repair of the corneal endothelium following mechanical damage

“…An improvement in the endothelial parameters was also shown in corneas that were first preserved under hypothermic conditions and then transferred for several days to OC (Camposampiero et al 2003). Despite these facts, there is no obvious superiority of one of the storage systems over the other, based on the similar clinical results achieved with grafts prepared by both methods (Rijneveld et al 1992;Frueh & Bo¨hnke 2000).…”

Overview of Short-Term and Intermediate-Term Corneal Storage Solution: Comparison of Clinical Outcomes and Need For Future Research

“…In addition, the activity of antibiotic is limited in refrigerated temperature. In a prospective study, Rijneveld et al 42 did not find any significant difference in visual acuity, central corneal thickness, and ECD for grafts stored in MK storage solution and organ culture. HLA-DR antigen is found to be decreased in the corneas preserved by organ culture.…”

Pan-Corneal Endothelial Viability Assessment: Application to Endothelial Grafts Predissected by Eye Banks

“…65 Interestingly, although we did not demonstrate it, the same observation can be made for series using 4°C stored corneas: 11% Ϯ 20% at 6 months postoperatively in the Cornea Donor Study. 66,67 Because no difference in either clinical results or ECD has been shown between 4°C and OC stored corneas, 65,68 we think our results could be extrapolated to 4°C storage, where SM performed in eye banks may have the same gap with viable ECD as does TLM in eye banks using OC. This remains to be investigated.…”

Organ culture, but not hypothermic storage, facilitates the repair of the corneal endothelium following mechanical damage

“…An improvement in the endothelial parameters was also shown in corneas that were first preserved under hypothermic conditions and then transferred for several days to OC (Camposampiero et al 2003). Despite these facts, there is no obvious superiority of one of the storage systems over the other, based on the similar clinical results achieved with grafts prepared by both methods (Rijneveld et al 1992;Frueh & Bo¨hnke 2000).…”

Overview of Short-Term and Intermediate-Term Corneal Storage Solution: Comparison of Clinical Outcomes and Need For Future Research

“…In addition, the activity of antibiotic is limited in refrigerated temperature. In a prospective study, Rijneveld et al 42 did not find any significant difference in visual acuity, central corneal thickness, and ECD for grafts stored in MK storage solution and organ culture. HLA-DR antigen is found to be decreased in the corneas preserved by organ culture.…”