Clinical aspects of human rabies in the state of Ceará, Brazil: an overview of 63 cases

Duarte, Naylê Francelino Holanda; Neto, Roberto da Justa Pires; Viana, Victoria Forte; Feijão, Levi Ximenes; Alencar, Carlos Henrique; Heukelbach, Jörg

doi:10.1590/0037-8682-0509-2021

Cited by 5 publications

(3 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Deaths from rabies are preventable through prompt post-exposure prophylaxis (PEP). In Brazil for example, a significant reduction in rabies mortality rates over the past 40 years was observed following the implementation of canine vaccination campaigns and the intensification of PEP 14 , 15 . The United States and some European regions have historically reduced and eliminated dog-mediated HR, thanks to the availability of PEP with vaccination and immunoglobulin 16 .…”

Section: Covid-19 Impact On Post-exposure Prophylaxis Worldwidementioning

confidence: 99%

“…Between 2010 and 2017, Brazil reported 188 HR cases, with a progressive and marked decline over those years 14 , 15 . From 2018 to 2021, only 15 HR cases were identified, most occurring before the COVID-19 pandemic.…”

Section: Rabies In Brazilmentioning

confidence: 99%

“…The former involved a 60-year-old man who sustained injuries from a bovine, in which the AgV3 variant was detected, while the latter concerned a 36-year-old man bitten two months prior by a non-human primate ( Callithrix jacchus ), potentially due to the new marmoset-related variant (AgV new). Ceará had not reported any cases of HR for seven years, with the most recent incident in 2016 involving a bat bite 14 , 15 . In 2022, an HR outbreak among indigenous children in Minas Gerais, Brazil, garnered the attention of health authorities.…”

Section: Rabies In Brazilmentioning

confidence: 99%

See 2 more Smart Citations

Human Rabies during the COVID-19 Pandemic: Insights into Rabies Worldwide and Brazil

Farias,

Caminha,

Perdigão Neto

et al. 2024

Rev. Soc. Bras. Med. Trop.

View full text Add to dashboard Cite

Human Rabies (HR) is a fatal zoonotic disease caused by lyssaviruses, with the rabies virus (RABV) identified as the causative agent. While the incidence of HR transmitted by dogs has decreased in Latin America, there has been a corresponding rise in transmission via wild animals. Given the lack of effective treatments and specific therapies, the management of HR relies on the availability of post-exposure prophylaxis and animal control measures. This review examines the dynamics and spread of HR during the global pandemic.

show abstract

Section: Covid-19 Impact On Post-exposure Prophylaxis Worldwidementioning

confidence: 99%

Section: Rabies In Brazilmentioning

confidence: 99%

Section: Rabies In Brazilmentioning

confidence: 99%

See 1 more Smart Citation

Human Rabies during the COVID-19 Pandemic: Insights into Rabies Worldwide and Brazil

Farias,

Caminha,

Perdigão Neto

et al. 2024

Rev. Soc. Bras. Med. Trop.

View full text Add to dashboard Cite

show abstract

Rabies virus variants from bats closely related to variants found in marmosets (Callithrix jacchus), a neglected source of human rabies infection in Brazil

de Sousa,

de Souza,

Tibo

et al. 2023

Journal of Medical Virology

View full text Add to dashboard Cite

Rabies is a fatal viral zoonosis caused by rabies virus (RABV). RABV infects the central nervous system and triggers acute encephalomyelitis in both humans and animals. Endemic in the Brazilian Northeast region, RABV emergence in distinct wildlife species has been identified as a source of human rabies infection and as such, constitutes a public health concern. Here, we performed post‐mortem RABV analyses of 144 encephalic tissues from bats sampled from January to July 2022, belonging to 15 different species. We identified phylogenetically distinct RABV from Phyllostomidae and Molossidae bats circulating in Northeastern Brazil. Phylogenetic clustering revealed the close evolutionary relationship between RABV viruses circulating in bats and variants hosted in white‐tufted marmosets, commonly captured to be kept as pets and linked to human rabies cases and deaths in Brazil. Our findings underline the urgent need to implement a phylogenetic‐scale epidemiological surveillance platform to track multiple RABV variants which may pose a threat to both humans and animals.

show abstract

Global burden of rabies in 204 countries and territories, from 1990 to 2019: results from the Global Burden of Disease Study 2019

Gan¹,

Hou²,

Wang³

et al. 2023

International Journal of Infectious Diseases

View full text Add to dashboard Cite

Clinical aspects of human rabies in the state of Ceará, Brazil: an overview of 63 cases

Cited by 5 publications

References 1 publication

Human Rabies during the COVID-19 Pandemic: Insights into Rabies Worldwide and Brazil

Human Rabies during the COVID-19 Pandemic: Insights into Rabies Worldwide and Brazil

Rabies virus variants from bats closely related to variants found in marmosets (Callithrix jacchus), a neglected source of human rabies infection in Brazil

Global burden of rabies in 204 countries and territories, from 1990 to 2019: results from the Global Burden of Disease Study 2019

Contact Info

Product

Resources

About