2012
DOI: 10.3109/02688697.2012.717983
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Abstract: The presence of steno-occlusive PCA lesions may be of pathogenic importance in MMD patients who develop both cerebral ischaemia and haemorrhage. The prevalence of this type of stroke in MMD patients is higher than expected, and further investigation in clinical settings is thus warranted.

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Cited by 21 publications
(12 citation statements)
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“…In our study, the gyral pattern was seen in 57% in 14 patients under 10 years but was not seen in adolescents. Coexistence of cerebral ischemia and hemorrhage at presentation has been very rarely reported in patients with MD [20][21][22]. In our study, only one adolescent, who presented with an acute hemorrhage on brain computed tomography at symptom onset, had a subsequent gyral ischemic infarction involving ipsilateral frontal lobe on a subsequent brain MRI.…”
Section: Discussionmentioning
confidence: 46%
See 1 more Smart Citation
“…In our study, the gyral pattern was seen in 57% in 14 patients under 10 years but was not seen in adolescents. Coexistence of cerebral ischemia and hemorrhage at presentation has been very rarely reported in patients with MD [20][21][22]. In our study, only one adolescent, who presented with an acute hemorrhage on brain computed tomography at symptom onset, had a subsequent gyral ischemic infarction involving ipsilateral frontal lobe on a subsequent brain MRI.…”
Section: Discussionmentioning
confidence: 46%
“…In our study, only one adolescent, who presented with an acute hemorrhage on brain computed tomography at symptom onset, had a subsequent gyral ischemic infarction involving ipsilateral frontal lobe on a subsequent brain MRI. Hishikawa et al reported that 10% of 92 patients between 5 and 55-years-of-age developed concomitant cerebral hemorrhage and ischemia [20]. Brain MRI findings in patients with MD have been described as a part of diagnostic guidelines for MD [11].…”
Section: Discussionmentioning
confidence: 99%
“…In addition, most of the symptoms occurred in the ischemic stroke after a hemorrhagic stroke. 9,15,16 These findings suggest that different stroke presentations in adult MMD may be associated with inherent factors. Bypass surgery may be helpful in reducing the risk of stroke development in adulthood-onset ischemic MMD, similar to childhood-onset MMD, whereas the effectiveness of bypass surgery for stroke prevention is still controversial in adult MMD with intracranial hemorrhage.…”
Section: Discussionmentioning
confidence: 86%
“…19 The PCA usually provides much collateral flow to the anterior circulation in moyamoya disease, and recent studies revealed a higher prevalence of ischemic and hemorrhagic stroke in patients with such PCA involvement. 7,22 However, any association between long-term outcomes and PCA involvement in moyamoya disease has not yet been closely examined.…”
mentioning
confidence: 99%