Clinical and laboratory investigations of active compression-decompression cardiopulmonary resuscitation

Survival with one versus three centimeters of active decompression during automated head-up CPR in a porcine cardiac arrest model

“…Prior studies have demonstrated that incomplete chest recoil impairs circulation, 34 , 35 whereas actively lifting the chest to or above the neutral position enhances hemodynamic and survival outcomes. 36 , 37 , 38 Active decompression during CPR with an ITD increases negative intrathoracic pressure, reduces right atrial and ventricular decompression pressures, and increases venous return and cardiac output. 32 , 36 , 37 , 38 , 39 When AL-3 cm during ACD-CPR is combined with an ITD, these effects are further amplified, leading to improved perfusion, circulation, and 1-year survival rates.…”

“… 36 , 37 , 38 Active decompression during CPR with an ITD increases negative intrathoracic pressure, reduces right atrial and ventricular decompression pressures, and increases venous return and cardiac output. 32 , 36 , 37 , 38 , 39 When AL-3 cm during ACD-CPR is combined with an ITD, these effects are further amplified, leading to improved perfusion, circulation, and 1-year survival rates. 12 , 24 , 40 More recent studies have shown that active chest wall lift above 1-cm during active decompression optimizes the physiological benefits of AHUP-CPR, by further increasing ventricular filling and cardiac output.…”

Survival with one versus three centimeters of active decompression during automated head-up CPR in a porcine cardiac arrest model

“…Prior studies have demonstrated that incomplete chest recoil impairs circulation, 34 , 35 whereas actively lifting the chest to or above the neutral position enhances hemodynamic and survival outcomes. 36 , 37 , 38 Active decompression during CPR with an ITD increases negative intrathoracic pressure, reduces right atrial and ventricular decompression pressures, and increases venous return and cardiac output. 32 , 36 , 37 , 38 , 39 When AL-3 cm during ACD-CPR is combined with an ITD, these effects are further amplified, leading to improved perfusion, circulation, and 1-year survival rates.…”

“… 36 , 37 , 38 Active decompression during CPR with an ITD increases negative intrathoracic pressure, reduces right atrial and ventricular decompression pressures, and increases venous return and cardiac output. 32 , 36 , 37 , 38 , 39 When AL-3 cm during ACD-CPR is combined with an ITD, these effects are further amplified, leading to improved perfusion, circulation, and 1-year survival rates. 12 , 24 , 40 More recent studies have shown that active chest wall lift above 1-cm during active decompression optimizes the physiological benefits of AHUP-CPR, by further increasing ventricular filling and cardiac output.…”

Active decompression during automated head-up cardiopulmonary resuscitation

“…Prior studies have demonstrated the irreversible consequences of continuously leaning on the chest and not allowing for full passive or active recoil to the neutral position [ 32 , 33 ]. Moreover, multiple studies have demonstrated that applying an active lift to bring the chest to the neutral chest position or above significantly improves hemodynamics and, when combined with an ITD, results in survival outcomes in animals and patients [ 8 , 9 , 34 – 40 ]. It is important to emphasize that in the current study, the chest was always actively lifted from the point of maximum compression to the neutral or resting position of the chest wall, even during the 0 cm lift portion of the protocol.…”

Die neuen Reanimationsleitlinien 2005 des European Resuscitation Council

“…Konsekutiv kann dann mit der nächsten Kompression (der künstlichen Systole) aufgrund eines besser vorgefüllten Ventrikels mehr Blut ausgeworfen werden [147]. Erste viel versprechende Ergebnisse hinsichtlich der Überlebenschan-cen bei mit ACD-CPR behandelten Patienten konnten in einer Cochrane-Analyse (n=4162) im Vergleich zur Standard-CPR nicht festgestellt werden [99].…”

Survival with one versus three centimeters of active decompression during automated head-up CPR in a porcine cardiac arrest model

“…Prior studies have demonstrated that incomplete chest recoil impairs circulation, 34 , 35 whereas actively lifting the chest to or above the neutral position enhances hemodynamic and survival outcomes. 36 , 37 , 38 Active decompression during CPR with an ITD increases negative intrathoracic pressure, reduces right atrial and ventricular decompression pressures, and increases venous return and cardiac output. 32 , 36 , 37 , 38 , 39 When AL-3 cm during ACD-CPR is combined with an ITD, these effects are further amplified, leading to improved perfusion, circulation, and 1-year survival rates.…”

“… 36 , 37 , 38 Active decompression during CPR with an ITD increases negative intrathoracic pressure, reduces right atrial and ventricular decompression pressures, and increases venous return and cardiac output. 32 , 36 , 37 , 38 , 39 When AL-3 cm during ACD-CPR is combined with an ITD, these effects are further amplified, leading to improved perfusion, circulation, and 1-year survival rates. 12 , 24 , 40 More recent studies have shown that active chest wall lift above 1-cm during active decompression optimizes the physiological benefits of AHUP-CPR, by further increasing ventricular filling and cardiac output.…”

Active decompression during automated head-up cardiopulmonary resuscitation

“…Prior studies have demonstrated the irreversible consequences of continuously leaning on the chest and not allowing for full passive or active recoil to the neutral position [ 32 , 33 ]. Moreover, multiple studies have demonstrated that applying an active lift to bring the chest to the neutral chest position or above significantly improves hemodynamics and, when combined with an ITD, results in survival outcomes in animals and patients [ 8 , 9 , 34 – 40 ]. It is important to emphasize that in the current study, the chest was always actively lifted from the point of maximum compression to the neutral or resting position of the chest wall, even during the 0 cm lift portion of the protocol.…”

Die neuen Reanimationsleitlinien 2005 des European Resuscitation Council

“…Konsekutiv kann dann mit der nächsten Kompression (der künstlichen Systole) aufgrund eines besser vorgefüllten Ventrikels mehr Blut ausgeworfen werden [147]. Erste viel versprechende Ergebnisse hinsichtlich der Überlebenschan-cen bei mit ACD-CPR behandelten Patienten konnten in einer Cochrane-Analyse (n=4162) im Vergleich zur Standard-CPR nicht festgestellt werden [99].…”

Survival with one versus three centimeters of active decompression during automated head-up CPR in a porcine cardiac arrest model

“…Prior studies have demonstrated that incomplete chest recoil impairs circulation, 34 , 35 whereas actively lifting the chest to or above the neutral position enhances hemodynamic and survival outcomes. 36 , 37 , 38 Active decompression during CPR with an ITD increases negative intrathoracic pressure, reduces right atrial and ventricular decompression pressures, and increases venous return and cardiac output. 32 , 36 , 37 , 38 , 39 When AL-3 cm during ACD-CPR is combined with an ITD, these effects are further amplified, leading to improved perfusion, circulation, and 1-year survival rates.…”

“… 36 , 37 , 38 Active decompression during CPR with an ITD increases negative intrathoracic pressure, reduces right atrial and ventricular decompression pressures, and increases venous return and cardiac output. 32 , 36 , 37 , 38 , 39 When AL-3 cm during ACD-CPR is combined with an ITD, these effects are further amplified, leading to improved perfusion, circulation, and 1-year survival rates. 12 , 24 , 40 More recent studies have shown that active chest wall lift above 1-cm during active decompression optimizes the physiological benefits of AHUP-CPR, by further increasing ventricular filling and cardiac output.…”

Active decompression during automated head-up cardiopulmonary resuscitation

“…Prior studies have demonstrated the irreversible consequences of continuously leaning on the chest and not allowing for full passive or active recoil to the neutral position [ 32 , 33 ]. Moreover, multiple studies have demonstrated that applying an active lift to bring the chest to the neutral chest position or above significantly improves hemodynamics and, when combined with an ITD, results in survival outcomes in animals and patients [ 8 , 9 , 34 – 40 ]. It is important to emphasize that in the current study, the chest was always actively lifted from the point of maximum compression to the neutral or resting position of the chest wall, even during the 0 cm lift portion of the protocol.…”

Die neuen Reanimationsleitlinien 2005 des European Resuscitation Council

“…Konsekutiv kann dann mit der nächsten Kompression (der künstlichen Systole) aufgrund eines besser vorgefüllten Ventrikels mehr Blut ausgeworfen werden [147]. Erste viel versprechende Ergebnisse hinsichtlich der Überlebenschan-cen bei mit ACD-CPR behandelten Patienten konnten in einer Cochrane-Analyse (n=4162) im Vergleich zur Standard-CPR nicht festgestellt werden [99].…”