2017
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Abstract: Background: The minimal stroke severity justifying endovascular intervention remains elusive. However, a significant proportion of patients presenting with large vessel occlusion stroke (LVOS) and mild symptoms go untreated and face poor outcomes. We aimed to evaluate the clinical outcomes of patients presenting with LVOS and low symptom scores (National Institutes of Health Stroke Scale [NIHSS] score ≤8) undergoing endovascular therapy (ET). Methods: We performed a retrospective analysis of a prospectively co… Show more

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Cited by 8 publications
(3 citation statements)
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References 23 publications
(32 reference statements)
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“…Prior retrospective analyses of patients with mildly symptomatic AIS due to LVO have found similar rates of good clinical outcomes between patients following MM or ET with 64-75% of patients living independently at 90 days and symptomatic ICH in 6-17% of patients. [6][7][8][9][10]17 A multicenter analysis has suggested that ET may be performed safely in these patients and may lead to improved outcomes over medical therapy. 11 However, the study utilized heterogenous pretreatment imaging criteria and is confounded by the inclusion of different treatment arms between different centers.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Prior retrospective analyses of patients with mildly symptomatic AIS due to LVO have found similar rates of good clinical outcomes between patients following MM or ET with 64-75% of patients living independently at 90 days and symptomatic ICH in 6-17% of patients. [6][7][8][9][10]17 A multicenter analysis has suggested that ET may be performed safely in these patients and may lead to improved outcomes over medical therapy. 11 However, the study utilized heterogenous pretreatment imaging criteria and is confounded by the inclusion of different treatment arms between different centers.…”
Section: Discussionmentioning
confidence: 99%
“…However, these prior studies suffer from heterogeneity in pre-treatment imaging, variability in triage with perfusion imaging, and comparisons between ET and medical management (MM) groups between different centers. [6][7][8][9][10][11][12]…”
Section: Introductionmentioning
confidence: 99%
“…In practice, EVT at the level of more distally located smaller vessels with thinner vessel walls can be technically more challenging, with potentially a higher risk of complications. Nevertheless, it is proven that EVT of more distal occlusions, i.e., isolated M2 occlusions, is just as safe and effective as EVT performed in proximal large vessel occlusions [50, 51]. Therefore, in specific cases presenting with a significant neurological deficit due to a strategic small vessel occlusion (e.g., patients with aphasia as a single symptom), EVT should be considered as a valuable treatment tool.…”
Section: Endovascular Treatment In Distal Occlusionsmentioning
confidence: 99%