ABSTRACTCONTEXT AND OBJECTIVES: Sickle cell disease (SCD) is the most common genetic disorder among people of African descent, affecting approximately 3,500 newborns each year in Brazil. Hydroxyurea (HU) is the only effective drug to treating patients with SCD, thereby reducing morbidity and mortality. The objective was to analyze the effects of HU on SCD patients at our institution.
DESIGN AND SETTING:Retrospective study conducted at a sickle cell centre in Ribeirão Preto, São Paulo, Brazil.
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