Clinical and EEG Estimates of Absence Seizure Frequency

Evaluation of absences and myoclonic seizures in adults with genetic (idiopathic) generalized epilepsy: a comparison between self‐evaluation and objective evaluation based on home video‐EEG telemetry

“…An additional reason for the underestimation we noted in 30% of our patients is that TAs tend to become less frequent and, in some patients, more inconspicuous with advancing age [15, 16]. Despite the rather noticeable paucity of subsequent relevant clinical research, these early clinical observations [15, 16] would suggest that monitoring protocols that are appropriate for drug‐naïve children and adolescents with absences [3] and in children with childhood absence epilepsy [6] are probably inadequate for seizure documentation and quantification in adults with persisting TA.…”

“…Overestimation of TA has been noted before [3], presumably because of over‐attentiveness related to either parental concerns that treatment is sub‐optimal or from a feeling of insecurity that possible absences may be missed. For example, momentary blinks or brief periods of natural absent‐mindedness may trigger false‐positive estimates.…”

Evaluation of absences and myoclonic seizures in adults with genetic (idiopathic) generalized epilepsy: a comparison between self‐evaluation and objective evaluation based on home video‐EEG telemetry

“…An additional reason for the underestimation we noted in 30% of our patients is that TAs tend to become less frequent and, in some patients, more inconspicuous with advancing age [15, 16]. Despite the rather noticeable paucity of subsequent relevant clinical research, these early clinical observations [15, 16] would suggest that monitoring protocols that are appropriate for drug‐naïve children and adolescents with absences [3] and in children with childhood absence epilepsy [6] are probably inadequate for seizure documentation and quantification in adults with persisting TA.…”

“…Overestimation of TA has been noted before [3], presumably because of over‐attentiveness related to either parental concerns that treatment is sub‐optimal or from a feeling of insecurity that possible absences may be missed. For example, momentary blinks or brief periods of natural absent‐mindedness may trigger false‐positive estimates.…”

Absence Seizure Detection Algorithm for Portable EEG Devices

“…It has long been recognized that long-term EEG monitoring is the most reliable method for absence detection ( 27 ). Parents notice only about 6% of daytime seizures, and very often, teachers are the ones who recognize the CAE/JEA beginning ( 28 ).…”

Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy: Initial monotherapy outcomes at 12 months

“…Clinical history and hyperventilation alone were not considered adequate to determine and confirm seizure freedom. Comparison of parental report of clinically obvious seizures with measures on EEG has found that parental report frequently underestimated the seizure burden by fivefold or 10‐fold (Browne et al., 1983). The office‐based hyperventilation test is associated with unacceptably high rates of false‐positive and false‐negative test results (North et al., 1990; Aicardi, 1994; Epstein et al., 1994; Wirrell et al., 1996).…”

Evaluation of absences and myoclonic seizures in adults with genetic (idiopathic) generalized epilepsy: a comparison between self‐evaluation and objective evaluation based on home video‐EEG telemetry

“…An additional reason for the underestimation we noted in 30% of our patients is that TAs tend to become less frequent and, in some patients, more inconspicuous with advancing age [15, 16]. Despite the rather noticeable paucity of subsequent relevant clinical research, these early clinical observations [15, 16] would suggest that monitoring protocols that are appropriate for drug‐naïve children and adolescents with absences [3] and in children with childhood absence epilepsy [6] are probably inadequate for seizure documentation and quantification in adults with persisting TA.…”

“…Overestimation of TA has been noted before [3], presumably because of over‐attentiveness related to either parental concerns that treatment is sub‐optimal or from a feeling of insecurity that possible absences may be missed. For example, momentary blinks or brief periods of natural absent‐mindedness may trigger false‐positive estimates.…”

Absence Seizure Detection Algorithm for Portable EEG Devices

“…It has long been recognized that long-term EEG monitoring is the most reliable method for absence detection ( 27 ). Parents notice only about 6% of daytime seizures, and very often, teachers are the ones who recognize the CAE/JEA beginning ( 28 ).…”

Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy: Initial monotherapy outcomes at 12 months

“…Clinical history and hyperventilation alone were not considered adequate to determine and confirm seizure freedom. Comparison of parental report of clinically obvious seizures with measures on EEG has found that parental report frequently underestimated the seizure burden by fivefold or 10‐fold (Browne et al., 1983). The office‐based hyperventilation test is associated with unacceptably high rates of false‐positive and false‐negative test results (North et al., 1990; Aicardi, 1994; Epstein et al., 1994; Wirrell et al., 1996).…”

Evaluation of absences and myoclonic seizures in adults with genetic (idiopathic) generalized epilepsy: a comparison between self‐evaluation and objective evaluation based on home video‐EEG telemetry

“…An additional reason for the underestimation we noted in 30% of our patients is that TAs tend to become less frequent and, in some patients, more inconspicuous with advancing age [15, 16]. Despite the rather noticeable paucity of subsequent relevant clinical research, these early clinical observations [15, 16] would suggest that monitoring protocols that are appropriate for drug‐naïve children and adolescents with absences [3] and in children with childhood absence epilepsy [6] are probably inadequate for seizure documentation and quantification in adults with persisting TA.…”

“…Overestimation of TA has been noted before [3], presumably because of over‐attentiveness related to either parental concerns that treatment is sub‐optimal or from a feeling of insecurity that possible absences may be missed. For example, momentary blinks or brief periods of natural absent‐mindedness may trigger false‐positive estimates.…”

Absence Seizure Detection Algorithm for Portable EEG Devices

“…It has long been recognized that long-term EEG monitoring is the most reliable method for absence detection ( 27 ). Parents notice only about 6% of daytime seizures, and very often, teachers are the ones who recognize the CAE/JEA beginning ( 28 ).…”

Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy: Initial monotherapy outcomes at 12 months

“…Clinical history and hyperventilation alone were not considered adequate to determine and confirm seizure freedom. Comparison of parental report of clinically obvious seizures with measures on EEG has found that parental report frequently underestimated the seizure burden by fivefold or 10‐fold (Browne et al., 1983). The office‐based hyperventilation test is associated with unacceptably high rates of false‐positive and false‐negative test results (North et al., 1990; Aicardi, 1994; Epstein et al., 1994; Wirrell et al., 1996).…”