Clindamycin for Intraincisional Antibiotic Prophylaxis in Dermatologic Surgery

The safety of Mohs surgery: A prospective multicenter cohort study

“…Measures to reduce wound infection vary and, though intraincisional/peri-incisional antibiotics are not used widely in Mohs surgery, randomized trials have shown they reduce the incidence of infection without reaching a significant systemic level. 10 Interestingly, the present study showed no difference in the rate of infection between patients given intraincisional/peri-incisional antibiotics and those not.…”

Do systemic antibiotics increase the survival of a full thickness graft on the nose?

“…10 Theoretically, use of topical or intra-incisional antibiotics can also be considered in the use of infection prevention. 11 As expected, the difference in survival of the graft between the groups became larger during the follow-up visits. After 5-7 days grafts are often pale or violaceous and critically perfused.…”

Prospective study of wound infections in Mohs micrographic surgery using clean surgical technique in the absence of prophylactic antibiotics

“…[5][6][7][8][9][10][11]13,15,16 Six of these studies include at least control arms where no antibiotic prophylaxis was used and the rates of SSIs remained low (0.72%-4.25%), providing strong evidence that antibiotics are not warranted for the majority of dermatologic surgery cases. [7][8][9][10]15,16 Yet, all of the studies to date used sterile technique at least during the wound reconstruction phase of the dermatologic surgeries. Our study is the first to identify the rate of SSI using clean surgical technique for all steps of MMS, including wound reconstruction, without antibiotic prophylaxis or topical antibiotics for postoperative wound care.…”